The rapid development of artificial intelligence (AI) in the medical field has become an important part of the learning process and health services. Preparing medical students as future healthcare professionals to understand, use, and implement AI responsibly is a crucial aspect. This level of readiness can vary depending on their knowledge, abilities, perceptions, and ethics in using AI. This study aims to determine the readiness of young medical students in the Surabaya area in using artificial intelligence based on these four domains, and to compare scores between first-year professional students and undergraduate students. This study used a quantitative descriptive design with a cross-sectional approach. The instrument used was the Medical Artificial Intelligence Scale for Medical Students questionnaire, which consists of four domains: knowledge, abilities, perceptions, and ethics. The study sample was first-year and second-year professional students of the Faculty of Medicine, Ciputra University. Data analysis was performed using descriptive statistics including mean values, standard deviations, and frequency distributions for each domain. The results showed that the total readiness scores for DM1 (89.95 ± 11.84) and DM2 (88.38 ± 8.85) showed a positive picture, with minimal mean differences. The knowledge and skills domain showed almost uniform values between the two groups, while the ethics domain had the highest stability with a very small mean difference. These findings indicate that the readiness of professional students at the Faculty of Medicine, Ciputra University, towards the use of AI shows a positive and relatively even picture at all levels.