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Dwi Wulandari
Universitas Muhammadiyah Surabaya

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PERAN “FANTASTIC FOUR” PADA GAGAL JANTUNG FRAKSI EJEKSI MENURUN Muhammad Perdana Airlangga; Dwi Wulandari
PROCEEDING UMSURABAYA Vol 1 No 3 (2023): Proceeding Series Fakultas Kedokteran
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/ps.v2i1.19416

Abstract

For all patients with heart failure with reduced ejection fraction (HFrEF), a multimodal approach is necessary, with a combination of numerous medications serving as the cornerstone for symptomatic and prognosis improvement. Newer treatment consist of Angiotensin-converting enzyme (ACE) inhibitors, angiotensin receptor/neprilysin inhibitors (ARNI), beta-blockers mineralocorticoid receptor antagonists (MRAs), and sodium-glucose co-transporter 2 (SGLT2) inhibitors demonstrated a highly significant and clinically relevant reduction in mortality and heart failure hospitalizations, as well as an improvement in quality of life.Keywords : heart failure, ejection fraction, ARNI, SGLT-2 inhibitor, ACE inhibitor, beta blocker, MRA