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All Journal Saintika Medika: Jurnal Ilmu Kesehatan dan Kedokteran Keluarga. Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya Journal of Islamic Medicine MAGNA MEDICA: Berkala Ilmiah Kedokteran dan Kesehatan Jurnal Implementa Husada Indonesian Journal of Medical Sciences and Public Health Jurnal Pengabdian Masyarakat Medika Jurnal Medis Umum
Muhammad Perdana Airlangga, Muhammad Perdana
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Biochemistry, Genetics & Molecular Biology Engineering Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Veterinary

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SEORANG PASIEN AIDS DENGAN EFUSI PERIKARD MASIF Airlangga, Muhammad Perdana; Aminuddin, Muhammad
Saintika Medika: Jurnal Ilmu Kesehatan dan Kedokteran Keluarga Vol 14, No 1 (2018): JUNI 2018
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (636.08 KB) | DOI: 10.22219/sm.Vol14.SMUMM1.6689

Abstract

Infeksi HIV sering dikaitkan dengan gangguan jantung. Namun demikian, keterlibatan jantung pada populasi pasien HIV sering kurang didiagnosis atau dikaitkan dengan salah pada proses penyakit non-jantung lainnya. Efusi perikardial (PE) tidak jarang ditemukan pada pasien dengan HIV / AIDS yang dilaporkan mempengaruhi hampir 5% pasien HIV. Telah dibuktikan bahwa tamponade jantung, keadaan darurat hemodinamik yang serius sebagai akibat efusi perikardial, tidak perlu dikaitkan dengan efusi besar tetapi dengan cepatnya akumulasi PE dan kurangnya kepatuhan kompensasi dalam ruang perikardial. Selain itu, tingkat keparahan PE pada pasien HIV / AIDS telah terbukti berkorelasi dengan prognosis buruk sebelum meluasnya penggunaan terapi antiretroviral (ART), meskipun demikian, implikasi prognostik PE tidak dapat ditentukan karena HAART telah mengubah riwayat alami PE. .Kata kunci : Efusi perikardial; Tamponade Jantung; HIV; AIDS.
Dilema Penggunaan Aspirin dan Proton Pump Inhibitor (PPI) Pada Pasien Gastroesophageal Reflux Disease Dengan Coronary Artery Disease (CAD) Prahastutik, Rizkia Hani; Airlangga, Muhammad Perdana; Ayu Rezkitha, Yudith Annisa; Irawati, Detti Nur
Journal of Islamic Medicine Vol 5, No 1 (2021): JOURNAL OF ISLAMIC MEDICINE EDISI MARET 2021
Publisher : Faculty of Medicine and Health Science, Universitas Islam Negeri Maulana Malik Ibrahim

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/jim.v5i1.11572

Abstract

Latar belakang: Gastroesofageal Reflux Disease (GERD) ini sering terjadi pada penderita Coronary Artery Disease (CAD) dengan keluhan nyeri dada. Oleh karena itu obat antiplatelet digabungkan dengan Proton Pump Inhibitor (PPI) untuk pencegahan dari efek samping aspirin dan pengobatan GERD itu sendiri. Karena efek samping pendarahan gastrointestinal yang disebabkan oleh aspirin, Proton Pump Inhibitors (PPI) juga bisa berpengaruh mengurangi ketersediaan hayati aspirin, sehingga mengurangi kerja aspirin. Tujuan : untuk menganalisis munculnya dilema pengobatan pada pasien Gastroesophageal Reflux Disease (GERD) dengan Coronary Artery Disease (CAD). Metode: Artikel-artikel ilmiah terpublikasi tentang Gastroesophageal Refluks Disease (GERD) dengan Coronary Artery Disease (CAD) dicari menggunakan kata kunci Gastroesophageal Reflux Disease, Coronary Artery Disease, Antiplatelet, Proton Pump Inhibitors. dengan mendapatkan jumlah artikel sebanyak 1144877 dan telah melalui skrining sesuai dengan kriteria inlusi menjadi 7 jurnal Hasil : Pada pasien kunci Gastroesophageal Reflux Disease (GERD) dengan Coronary Artery Disease (CAD) Proton Pump Inhibitors (PPIs) sering dikombinasikan dengan antiplatelet yang telah terbukti secara efektif mengurangi resiko komplikasi pada gastrointestinal pada pasien. Namun, pada beberapa penelitian pemberian PPI akan mengurangi efek kemanjuran dari antiplatelet aspirin Kesimpulan: Penggunaan PPI pada GERD dianjurkan untuk digunakan dalam jangka pendek,karena penggunaan jangka panjang pada PPI meningkatkan resiko infark miokard, gagal ginjal, dan demensia. Pertimbangan pada resiko dan manfaat dengan mengkaji faktor resiko dari ganstrointestinal perlu diperhatikanKata kunci : Antiplatelet, Coronary Artery Disease, Gastroesophageal Proton Pump Inhibitors Reflux Disease,
The Effect of Oral Sildenafil on the Decrease in the Degree of Pulmonary Artery Systolic Pressure in PPHN Infants at Siti Khodijah Muhammadiyah Hospital Sepanjang Afif, Muhammad; Airlangga, Muhammad Perdana; Yuliyanasari, Nurma; Djalilah, Gina Noor
MAGNA MEDIKA: Berkala Ilmiah Kedokteran dan Kesehatan Vol 8, No 1 (2021): February
Publisher : APKKM (Muhammadiyah Medical and Health Education Association)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1786.194 KB) | DOI: 10.26714/magnamed.8.1.2021.18-28

Abstract

Background: Persistent Pulmonary Hypertension of the Newborn (PPHN) is a condition of the failure to decrease pulmonary artery pressure, so that blood pressure in the lungs remains high, as in a fetus. PPHN cases are 2-6 of 1000 live births and responsible for 10% of confirmed deaths in the neonatal intensive care unit (NICU). Sildenafil is vasodilator that can be used to reduce pulmonary artery systolic pressure (PASP), morbidity, and mortality in PPHN infants.Objective: To analyze the effect of sildenafil on decrease the severity of pulmonary artery systolic pressure in PPHN infants.Method: This is an analytic observational study with cross-sectional design. The samples were collected using consecutive sampling on 30 PPHN infant patients in 2018. The data were collected from medical records of PPHN infant patients, then assessing the severity value of PASP which obtained from echocardiography result. The severity of PASP is classified into normal (PASP≤35 mmHg), mild (PASP36-45 mmHg), moderate (PASP 45-60 mmHg), and severe (PASP>60 mmHg)Results: This study showed that 27 PPHN infant patients have decreased PASP level to normal, previously from mild 7 infants (23.3%), moderate 16 infants (53.3%), and severe 4 infants (13%), after being given oral sildenafil. There were 1 (3.3%) infant patient remained severes, 1 (3.3%) patient was decreased from severe to moderate, and 1 patient (3.3%) was decreased from severe to mild. The p value <0.05 was obtained, so oral sildenafil significantly decreased the PASP severity in PPHN infants patients.Conclusion: There is a beneficial effect of oral sildenafil on decreasing the severity of pulmonary artery systolic pressure in PPHN infants at the NICU of Siti Khodijah Muhammadiyah Hospital Sepanjang.
SEORANG PASIEN AIDS DENGAN EFUSI PERIKARD MASIF Muhammad Perdana Airlangga; Muhammad Aminuddin
Saintika Medika Vol. 14 No. 1 (2018): JUNI 2018
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/sm.Vol14.SMUMM1.6689

Abstract

Infeksi HIV sering dikaitkan dengan gangguan jantung. Namun demikian, keterlibatan jantung pada populasi pasien HIV sering kurang didiagnosis atau dikaitkan dengan salah pada proses penyakit non-jantung lainnya. Efusi perikardial (PE) tidak jarang ditemukan pada pasien dengan HIV / AIDS yang dilaporkan mempengaruhi hampir 5% pasien HIV. Telah dibuktikan bahwa tamponade jantung, keadaan darurat hemodinamik yang serius sebagai akibat efusi perikardial, tidak perlu dikaitkan dengan efusi besar tetapi dengan cepatnya akumulasi PE dan kurangnya kepatuhan kompensasi dalam ruang perikardial. Selain itu, tingkat keparahan PE pada pasien HIV / AIDS telah terbukti berkorelasi dengan prognosis buruk sebelum meluasnya penggunaan terapi antiretroviral (ART), meskipun demikian, implikasi prognostik PE tidak dapat ditentukan karena HAART telah mengubah riwayat alami PE. .Kata kunci : Efusi perikardial; Tamponade Jantung; HIV; AIDS.
Role Of Inhaled Nitric Oxides In Pregnancy With Eisenmenger Syndrome Muhammad Anas; Nenny Triastuti; Muhammad Perdana Airlangga
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 4, No 1 (2020)
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (177.512 KB) | DOI: 10.30651/jqm.v4i1.3478

Abstract

ABSTRACTEisenmenger Syndrome (ES) is congenital heart disease with pulmonary hypertension and shunting turning from right to left. The resistance of pulmonary vascular more than 7.5 mmHg/L/min. The right ventricle and pulmonary artery always enlarge. During pregnancy, there will be hemodynamic changes that will affect the ES. It can be understood the possible dangers that can occur, like right heart failure; an increase in pulmonary arteries or the aggravation of pulmonary hypertension because there is no decrease in pulmonary resistance; A sudden decrease in venous return in supine hypotension syndrome can cause a relative increase in pulmonary arterial pressure so as to aggravate pulmonary hypertension and reverse shunting.Physiological effects of inhaled nitric oxide (INO) therapy cause selective pulmonary vasodilation: Hypoxia alveoli causes reversible vasoconstriction, thereby increasing pulmonary wedge pressure. INO can lower it. Moderate cardiac output and systematic arterial pressure are not affected; Selective in pulmonary because it is activated by hemoglobin; Selective vasodilation in the ventilated area, local hypoxia alveoli constricts the surrounding vascular tissue and redistributes blood flow to the ventilated lungs better and higher intraalveolar oxygen pressure. INO enhances this mechanism by increasing blood flow through a well-ventilated lung; Bronchodilators; Pulmonary surfactant, The combination of high concentrations of inspired oxygen and high concentrations of INO reduces the minimum surfactant surface tension.Keywords: Inhalation Nitric Oxides, Pregnancy, Eisenmenger Syndrome
Diagnosis dan Tatalaksana Tromboemboli pada Kehamilan Muhammad Perdana Airlangga
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 1, No 02 (2017)
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (191.789 KB) | DOI: 10.30651/qm.v1i02.633

Abstract

Venous thromboembolism is both more common and more complex to diagnose in patients who are pregnant than in those who are not pregnant. Pulmonary embolism and deep-vein thrombosis are the two components of a single disease called venous thromboembolism. Pulmonary embolism is the leading cause of maternal death in the developed world. Delayed diagnosis, delayed or inadequate treatment, and inadequate thromboprophylaxis account for many of the deaths due to venous thromboembolism. Successful strategies for the management of venous thromboembolism in nonpregnant patients have been established. However, many of the recommendations for the treatment of pregnant patients who have venous thromboembolism are not based on high-quality data; rather, they are derived from observational studies and extrapolation from studies involving nonpregnant patients. The purpose of this review is to provide a practical approach to the diagnosis, management, and prevention of venous thromboembolism in pregnant patients.
Antibiotik Profilaksis Pada Penyakit Jantung Musa Ghufron; Muhammad Perdana Airlangga
MAGNA MEDIKA: Berkala Ilmiah Kedokteran dan Kesehatan Vol 6, No 1 (2019): February
Publisher : Universitas Muhammadiyah Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (677.746 KB) | DOI: 10.26714/magnamed.6.1.2019.38-50

Abstract

Prophylactic Antibiotics in Heart DiseaseInfective endocarditis (IE) is an uncommon but lifethreatening infection. Despite advances in diagnosis, antimicrobial therapy, surgical techniques, and management of complications, patients with IE still have high morbidity and mortality rates related to this condition. Since the last American Heart Association (AHA) publication on prevention of IE in 1997, many authorities and societies, as well as the conclusions of published studies, have questioned the efficacy of antimicrobial prophylaxis to prevent IE in patients who undergo a dental, gastrointestinal (GI), or genitourinary (GU) tract procedure and have suggested that guidelines should be revised
Efektivitas Biaya Sacubitril / Valsartan dalam Mengurangi Rehospitaliasasi pada Pengobatan Gagal Jantung dengan Fraksi Ejeksi Berkurang Dibandingkan dengan Penggunaan Obat Golongan Ace Inhibitor Kharisma Sukma Nanda; Muhammad Perdana Airlangga; Nurma Yuliyanasari; Yudith Annisa Ayu Rezkitha
JURNAL IMPLEMENTA HUSADA Vol 2, No 1 (2021)
Publisher : UMSU

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/jih.v2i1.6950

Abstract

Gagal jantung merupakan masalah kesehatan masyarakat  dengan angka morbiditas dan mortalitas yang cukup besar, serta risiko kematian yang tinggi  pada negara maju maupun negara berkembang, sehingga membutuhkan manajemen terapi yang tepat untuk mengurangi morbiditas dan mortalitas. ACEI / ARB adalah standar perawatan yang biasa digunakan selama ini, namun sacubitril / valsartan banyak dibicarakan dan memberikan resiko kematian yang lebih rendah serta mengurangi rehospitalisasi pada pasien gagal jantung dibandingkan dengan penggunaan ACEI. Oleh karena itu, sacubitril / valsartan cenderung lebih hemat biaya dibandingkan dengan ACEI (standar perawatan saat ini). Tujuan penulisan ini untuk mengetahui efektivitas biaya sacubitril / valsartan dibandingkan dengan enalapril (ACEI) dalam pengobatan gagal jantung dengan fraksi ejeksi berkurang.
Usage of Inhaled Nitric Oxides in Cases of Eisenmenger Syndrome Nenny Triastuti; Muhammad Perdana Airlangga; Muhammad Anas
Indonesian Journal of Medical Sciences and Public Health Vol 1 No 1 (2020)
Publisher : Future Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (254.131 KB) | DOI: 10.11594/ijmp.01.01.03

Abstract

Eisenmenger Syndrome is congenital heart disease with pulmonary hypertension and shunting turning from right to left. The resistance of pulmonary vascular more than 7.5 mmHg/L/min. The right ventricle and pulmonary artery always enlarge. Physiological effects of inhaled nitric oxide therapy cause selective pulmonary vasodilation: Hypoxia alveoli causes reversible vasoconstriction, thereby increasing pulmonary wedge pressure. Inhaled nitric oxide can lower it. Moderate cardiac output and systematic arterial pressure are not affected; Selective in pulmonary because it is activated by hemoglobin; Selective vasodilation in the ventilated area, local hypoxia alveoli constricts the surrounding vascular tissue and redistributes blood flow to the ventilated lungs better and higher intraalveolar oxygen pressure. Inhaled nitric oxide enhances this mechanism by increasing blood flow through a well-ventilated lung; Bronchodilators; Pulmonary surfactant, The combination of high concentrations of inspired oxygen and high concentrations of Inhaled nitric oxide reduces the minimum surfactant surface tension.
The Effect of Dobutamine Administration on Oxygen Saturation in Infant's Persistent Pulmonary Hypertension of The Newborn (PPHN) Itaqullah, Yusfa Iswinda; Airlangga, Muhammad Perdana; Triastuti, Nenny; Djalilah, Gina Noor; Anas, Muhammad
MAGNA MEDICA Berkala Ilmiah Kedokteran dan Kesehatan Vol 9, No 2 (2022): August
Publisher : Universitas Muhammadiyah Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26714/magnamed.9.2.2022.147-154

Abstract

Background: PPHN of infants are severe cases because the rate of disability and death in infants is relatively high, reaching around 10-20% of cases. Therefore, prompt, accurate, and rational management is needed to reduce cases number of records and deaths. The incidence of PPHN is 2-6 out of 1000 live births; in Surabaya, the incidence was 42 babies per 1000 live births from April to September 2017. Dobutamine is an effective therapy that can support good morbidity and mortality. Therefore, therapeutic options in infants with PPHN in the form of dobutamine are often used.Objective: To determine the effect of dobutamine administration on oxygen saturation in infants with persistent pulmonary hypertension of the newborn (PPHN)Method: A cross-sectional design with a consecutive sampling of 50 infants with PPHN who received dobutamine therapy at the Hospital of Siti Khodijah Muhammadiyah Sepanjang. Data collection using medical records. Results: The average increase in oxygen saturation before and after being given dobutamine was 36.0%. No difference in the increase in oxygen saturation based on the duration of dobutamine administration. The dobutamine dose's effect on the oxygen saturation increase in infants with PPHN.Conclusion: The results of this study indicate a significant effect of dobutamine administration on increasing oxygen saturation in PPHN infants.
Co-Authors A.A. Ketut Agung Cahyawan W Aziza, Nurita Gani, Rima January Putri Ridwan Gina Noor Djalilah Heriyanto, Mochammad Junaidy Irawati, Detti Nur Itaqullah, Yusfa Iswinda Kharisma Sukma Nanda Levani , Yelvi M. Mansyur Romi Meddy Setiawan Mitayani Purwoko, Mitayani Muhammad Afif Muhammad Aminuddin Muhammad Anas Muhammad Anas Musa Ghufron Nenny Triastuti Novitasari, Erlina Krisdianita Nugraha, George Hagi Nurma Yuliyanasari, Nurma Pandhita, Gea Prahastutik, Rizkia Hani Prakoso, Denny Anggoro Putra, Chendra Perdana Rudiyanto, Waluyo Sriningsih, Solikah Sukarno, Rizky Triutami SULISTIYANI SULISTIYANI Tubarad, Gladys Dwiani Tinovella Yanuarita Tursinawati, Yanuarita Yudith Annisa Ayu Rezkitha, Yudith Annisa Ayu Yulinasari , Nurma