<![CDATA[Abstrak Terapi farmakologi diabetes melitus (DM) perlu digunakan secara tepat dan aman, tetapi perbedaan jadwal minum obat, risiko hipoglikemia, dan cara penyimpanan insulin masih berpotensi menimbulkan kesalahan pengobatan di masyarakat. Kegiatan pengabdian ini bertujuan memperkuat pengetahuan warga RW 08 Kelurahan Klender, Jakarta Timur, mengenai DM dan penggunaan obat antidiabetes. Kegiatan melibatkan pengurus RW 08 dan kelompok PKK sebagai mitra, dengan 15 peserta berusia 35–60 tahun, dan dilaksanakan pada 10 Juni 2026 melalui ceramah interaktif, media visual, contoh terapi, serta diskusi mengenai metformin, glimepiride, acarbose, insulin, hipoglikemia, kepatuhan, dan konsultasi sebelum mengubah dosis. Evaluasi menggunakan rancangan satu kelompok pre-test–post-test dengan 10 soal pilihan ganda, dianalisis secara deskriptif dan dilengkapi uji eksak Wilcoxon dua sisi. Rata-rata skor meningkat dari 97,33 (pre-test) menjadi 100,00 (post-test); tiga peserta (20,0%) meningkat, 12 peserta (80,0%) mempertahankan skor maksimum, dan tidak ada yang menurun. Jumlah jawaban benar meningkat dari 146 menjadi 150 dari 150 kemungkinan jawaban, dengan uji Wilcoxon menghasilkan p = 0,250. Hasil ini menunjukkan bahwa edukasi berhasil memperbaiki jawaban yang sebelumnya belum tepat dan memperkuat pengetahuan segera setelah kegiatan, meskipun perubahan belum bermakna secara statistik karena skor awal sudah sangat tinggi (ceiling effect). Evaluasi lanjutan diperlukan untuk menilai retensi pengetahuan, perilaku penggunaan obat, dan kepatuhan. Kata kunci: diabetes melitus; terapi farmakologi; literasi obat; edukasi kesehatan; pengabdian masyarakat Abstract Diabetes mellitus requires appropriate and safe pharmacological therapy; however, differences in administration schedules, the risk of hypoglycemia, and insulin storage practices may still lead to medication errors in the community. This community service activity aimed to strengthen the knowledge of residents of RW 08, Klender Urban Village, East Jakarta, regarding diabetes mellitus and the use of antidiabetic medicines. The activity involved the RW 08 committee and the PKK women's group as partners, with 15 participants aged 35–60 years, and was conducted on 10 June 2026 through an interactive lecture, visual media, therapy examples, and discussion on metformin, glimepiride, acarbose, insulin, hypoglycemia, adherence, and consultation before dose changes. Evaluation used a one-group pre-test–post-test design with a 10-item multiple-choice questionnaire, analyzed descriptively and supplemented with a two-sided exact Wilcoxon test. The mean score increased from 97.33 (pre-test) to 100.00 (post-test); three participants (20.0%) improved, 12 (80.0%) maintained the maximum score, and none declined. Correct answers increased from 146 to 150 out of 150 possible responses, with the Wilcoxon test yielding p = 0.250. These results indicate that the education corrected previously inaccurate responses and strengthened immediate knowledge, although the change was not statistically significant because baseline scores were already very high (ceiling effect). Follow-up evaluation is needed to assess knowledge retention, medication-use behavior, and adherence. Keywords: diabetes mellitus; pharmacological therapy; medication literacy; health education; community service ]]>
