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All Journal International Journal of Health Science Proceeding of The International Conference on Health Sciences and Nursing
Siti Saharah Abdullah
Institut Ilmu Kesehatan Pelamonia Makassar
Health Professions Public Health Social Sciences

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Formulation and Evaluation of Hydrogel Preparations from Jeneponto Horse Oil (Equus caballus) Siti Saharah Abdullah; A. Asmawati Saad; Taufiq Dalming; Dwi Resky Lestari
International Journal Of Health Science Vol. 5 No. 3 (2025): November : International Journal of Health
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/ijhs.v5i3.6275

Abstract

Horse oil, traditionally used as a medicinal remedy, contains essential amino acids that contribute to the repair of bones, muscle tissues, and skin, particularly in wound healing. Hydrogel preparations serve as topical wound dressings that provide a cooling effect, reduce inflammation, and support faster wound recovery. The aim of this research was to develop and evaluate the stability of a hydrogel formulated with horse oil (Equus caballus). The study involved heating horse fat at 105°C for two hours using an oven, followed by formulating the extracted oil into a hydrogel with a sodium carboxymethyl cellulose (NaCMC) base. The preparation underwent several tests including organoleptic, homogeneity, pH, spreadability, adhesion, viscosity, and stability evaluations. Results showed that formulations F1, F2, and F3 satisfied all evaluation criteria and maintained stability without changes in physical characteristics or pH levels.
Formulation And Physical Stability Testing Of Emulgel Preparation Of Rainbow Leaf Extract (Eucalyptus Deglupta Blume) With Combination Of Carbopol 940 And Hpmc Gelling Agent Concentrations Siti Saharah Abdullah; Taufiq Dalming; Ferawati Fajrin Abidin
Proceeding of the International Conference on Health Sciences and Nursing Vol. 2 No. 1 (2025): Proceeding of the International Conference on Health Sciences and Nursing
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/ichsn.v2i1.60

Abstract

Rainbow leaves are known to have antibacterial and anti-inflammatory activities, so they have the potential to be developed in the form of practical and comfortable topical emulgel preparations. This study aims to formulate and evaluate the physical stability of rainbow leaf extract emulgel preparations (Eucalyptus deglupta Blume) with variations in the combination of gelling agent concentrations Carbopol 940 and HPMC. Three emulgel formulas were made with different concentrations of Carbopol 940 and HPMC, then evaluated through organoleptic tests, homogeneity, pH, spreadability, adhesion, viscosity, and physical stability tests using the freeze-thaw method for 6 cycles. The evaluation results showed that all formulas met good physical parameters, with formula F1 (Carbopol 940 0.5% and HPMC 1.5%) showing the most optimal results in terms of viscosity, spreadability, and adhesion. Thus, the combination of Carbopol 940 and HPMC at optimal concentration can produce a physically stable rainbow leaf extract emulgel preparation that is suitable for topical application.
Co-Authors A. Asmawati Saad Dwi Resky Lestari Ferawati Fajrin Abidin Taufiq Dalming