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All Journal International Journal of Health and Pharmaceutical (IJHP)
Putu Bayu Triguna, I
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Nursing Public Health

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Dysphagia Improvement Following Sublingual Nifedipine Administration in Long-Segment Esophageal Stricture: A Case Report Jonathan, Steven; Putu Bayu Triguna, I; Giri Prathiwindya, Gde; Made Suma Wirawan, I
International Journal of Health and Pharmaceutical (IJHP) Vol. 6 No. 1 (2026): February 2026
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v6i1.504

Abstract

Dysphagia is a difficulty in swallowing either solid food or liquid. Esophageal stricture being one of the most common causes of dysphagia can be caused by inflammation, fibrosis, or neoplasia damaging the esophageal lumen. If left untreated, dysphagia can lead to malnutrition, aspiration, and decreased quality of life. Another common cause of dysphagia is esophageal motility disorder, an impairment in peristalsis of the esophageal. Calcium channel blockers such as nifedipine have been reported to improve dysphagia and may serve as alternative therapy while waiting for endoscopic intervention. A 27-year-old man presented with a two-month history of progressive dysphagia to solids, semisolids, and liquids, after an episode of hematemesis. Esophagogram showed esophageal stricture with impaired peristaltic. Contrast-enhanced CT result was suggestive of an intraluminal esophageal stricture. The patient was given sublingual nifedipine before meals as an alternative therapy while waiting for endoscopic intervention, and showed gradual sympomatic improvement. Dysphagia caused by long-segment esophageal stricture can be exacerbated by secondary motility disorder. While definitive treatment requires endoscopic intervention, sublingual nifedipine offered effective short-term symptomatic relief by reducing esophagogastric junction pressure and improving bolus transit through the narrowed lumen.
Optimizing Palliative Management For End-of-Life Elderly Patient With Non-Hodgkin Lymphoma : A Case Report Jonathan, Steven; Ravelia Tiffany Subroto, Devina; Putu Bayu Triguna, I
International Journal of Health and Pharmaceutical (IJHP) Vol. 6 No. 1 (2026): February 2026
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v6i1.518

Abstract

Diffuse Large B-Cell Lymphoma (DLBCL) is the most common type of non-Hodgkin’s lymphoma (NHL) in the elderly population. DLBCL is potentially curable with immunochemotherapy but becomes more difficult to cure as patients get older leading to poor prognosis. Palliative care is essential for patients with this condition to relieve their suffering and improve their quality of life. Treatment strategies of DLBCL in elderly patients remain a challenge for physicians and the patients. An 87-year-old male presented with difficulty swallowing for the past four months, worsened since last week. Throat pain, obstruction sensation, and confined to bed due to weakness. The patient has been diagnosed with DLBCL and refused chemotherapy. Dark-colored residue was observed in the nasogastric tube. There is an enlargement of right cervical lymph-node. His laboratory workup shows Hb 8,9mg/dL, histopathological of the oropharyngeal tissue showed Diffuse Large B-Cell Lymphoma, activated B-Cell subtype. Patient was treated through multidisciplinary approach to improve overall condition and his quality of life. The management of elderly patients with DLBCL requires multidisciplinary approach that considers patient preferences and quality of life. Elderly Prognostic Index are needed to evaluate patient condition, prognosis, and guide therapeutic decisions. Palliative therapy is an approach aimed at improving the quality of life of patients facing life-threatening illness through early identification and comprehensive management of pain, physical, psychosocial, and spiritual problems. Management of DLBCL in elderly patients requires balancing risks and benefits considering frailty, comorbidities, and overall functional status. Regardless of therapeutic choice, palliative and supportive care should be provided through a multidisciplinary approach to relieve suffering and preserve quality of life. Treatment decisions should be made involving the patient and their family, focusing on the ultimate goals of care in accordance to their wishes.
Co-Authors Giri Prathiwindya, Gde Jonathan, Steven Made Suma Wirawan, I Ravelia Tiffany Subroto, Devina