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Muhammad Fakhawarizmi
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Nursing Public Health

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Korelasi Nilai SPF dan Aktivitas Antioksidan Fraksi Etil Asetat Daun Bandotan (Ageratum conyzoides L.) Muhammad Fakhawarizmi; Danang Raharjo
Jurnal Kesehatan Amanah Vol. 10 No. 1 (2026): Mei: Jurnal Kesehatan Amanah
Publisher : Universitas Muhammadiyah Manado

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57214/jka.v10i1.1051

Abstract

Indonesia, as a tropical country, has high ultraviolet (UV) radiation intensity, which increases the risk of skin damage due to oxidative stress. This study aimed to determine the correlation between Sun Protection Factor (SPF) values and antioxidant capacity of the ethyl acetate fraction from bandotan leaves (Ageratum conyzoides L.). The study involved extraction by maceration using 96% ethanol, liquid-liquid fractionation, phytochemical screening, antioxidant activity testing using the ABTS method, and SPF value determination by UV-Vis spectrophotometry. The results showed that the ethyl acetate fraction exhibited the highest antioxidant activity with an IC₅₀ value of 21.726 ppm (very strong category) and the highest SPF value of 23.28 (ultra protection category). Statistical analysis indicated a significant positive correlation between antioxidant capacity and SPF values, with a correlation coefficient (R) of 0.647 and a coefficient of determination (R²) of 0.418 (p < 0.05). This study demonstrates that the ethyl acetate fraction of bandotan leaves has potential to be developed as a natural sunscreen ingredient with high antioxidant activity.
Co-Authors Danang Raharjo