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Regita Azzahra Nasution
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Biochemistry, Genetics & Molecular Biology Economics, Econometrics & Finance Education Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary

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KARDIOMIOPATI DIABETIK Regita Azzahra Nasution
Integrative Perspectives of Social and Science Journal Vol. 3 No. 02 Februari (2026): Integrative Perspectives of Social and Science Journal
Publisher : PT Wahana Global Education

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Abstract

Kardiomiopati diabetik merupakan salah satu komplikasi kardiovaskular penting pada diabetes melitus yang ditandai oleh perubahan struktural dan fungsional miokard tanpa adanya penyakit arteri koroner, hipertensi, maupun kelainan katup jantung yang signifikan. Kondisi ini berkembang secara progresif dan sering kali bersifat subklinis pada tahap awal, sehingga berkontribusi terhadap meningkatnya risiko gagal jantung pada pasien diabetes. Artikel review ini bertujuan untuk membahas konsep kardiomiopati diabetik secara komprehensif, meliputi definisi, epidemiologi, faktor risiko, mekanisme patofisiologi, pendekatan diagnostik, serta strategi terapi terkini. Berbagai mekanisme patogenetik terlibat dalam perkembangan kardiomiopati diabetik, termasuk hiperglikemia kronik, resistensi insulin, lipotoksisitas miokard, stres oksidatif, disfungsi mitokondria, aktivasi neurohormonal, dan perubahan struktural miokard. Diagnosis kardiomiopati diabetik masih menjadi tantangan karena keterbatasan gejala klinis spesifik, sehingga pemeriksaan pencitraan jantung dan biomarker molekuler memiliki peran penting dalam deteksi dini. Penatalaksanaan kardiomiopati diabetik memerlukan pendekatan multidisiplin yang mencakup modifikasi gaya hidup, kontrol glikemik optimal, serta terapi kardiovaskular berbasis bukti. Pemahaman yang lebih mendalam mengenai kardiomiopati diabetik diharapkan dapat mendukung upaya pencegahan, diagnosis dini, dan penatalaksanaan yang lebih efektif guna menurunkan morbiditas dan mortalitas pada pasien diabetes melitus.
EFFORTS MANAGEMENT OF TINEA CORPORIS IN A 16-YEARS-OLD FEMALE PATIENT THROUGH A FAMILY MEDICINE APPROACH AT KUTA MAKMUR PRIMARY HEALTH CENTER, NORTH ACEH REGENCY Regita Azzahra Nasution
Jurnal Medika Hutama Vol. 7 No. 3 April (2026): Jurnal Medika Hutama
Publisher : Yayasan Pendidikan Medika Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.66940/jmh.v7i3 April.798

Abstract

Patient An. R, 16 years old came to the Kutamakmur Health Center General Polyclinic with complaints of itching in the buttocks about 3 months ago and it has been aggravating since the last 10 days. Initially the complaint appears in the buttocks (buttocks) then slowly extends to the groin. Most of these complaints also appear in the facial area. Initially, the patient felt itching and began to scratch the itchy part so that the bleeding left spots and was felt to be wider and in some parts it looked red with a fairly clear border and accompanied by fine scales. These complaints are quite disruptive to the patient's daily activities. The patient used the same towel as his family member, namely the patient's brother. The patient's brother is a student of the Islamic boarding school who suffers from similar complaints. On physical examination, TD 110/90 mmHg, HR78 x/min, RR 20 x/min, T 36.8°C. On examination of the facial region, eflorescence was seen in the form of hypopigmentation patches and erythematose with firm borders, accompanied by central healing and raised edges with fine squamas. The patient was given therapy, namely ketoconazole cream and oral. Primary data was obtained through anamnesis and physical examination by conducting home visits, filling out family folders, and filling out patient files. The assessment is carried out based on the initial holistic diagnosis, process, and end of the visit, Interventions carried out include education on the importance of clean and healthy living behaviors, avoiding risk factors, adherence to taking medication and avoiding complications that can occur due to tinea corporis.
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