Article Per Year (5 Year)
p-Index From 2021 - 2026
0.23
P-Index
This Author published in this journals
All Journal Jurnal Komplikasi Anestesi
Febri, Rafli Nur
Unknown Affiliation
Medicine & Pharmacology

Published : 1 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search

 1 
Intraoperative Anaphylaxis Reaction Due to Suspected Anesthesia Agent Sukmono, Raden Besthadi; Febri, Rafli Nur
Jurnal Komplikasi Anestesi Vol 13 No 1 (2025)
Publisher : This journal is published by the Department of Anesthesiology and Intensive Therapy of Faculty of Medicine, Public Health and Nursing, in collaboration with the Indonesian Society of Anesthesiology and Intensive Therapy , Yogyakarta Special Region Br

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jka.v13i1.14971

Abstract

Background: Intraoperative anaphylaxis is a life-threatening condition that may present atypically without cutaneous or respiratory manifestations, making early diagnosis challenging. Case Presentation: A 24-year-old male (ASA II) with sinus bradycardia and three previous uneventful general anesthetics underwent left auricular mass extirpation under general anesthesia. Approximately 90 minutes after induction, the patient developed sudden tachycardia despite minimal surgical stimulation. No additional epinephrine infiltration had been administered. Body temperature was normal and sevoflurane MAC was 0.7. Initial management included a 200 mL crystalloid fluid challenge, fentanyl 2 µg/kg IV bolus, and reduction of sevoflurane MAC to 0.5; however, tachycardia persisted and severe hypotension ensued (from 100/60 mmHg to 50/30 mmHg). No rash, bronchospasm, or fever was observed. Suspected intraoperative anaphylaxis was treated with epinephrine 0.1 mg IV (two doses), 500 mL crystalloid bolus, and supine positioning. Tachycardia resolved after the first epinephrine dose, and blood pressure improved after the second dose. Conclusion: This case highlights that intraoperative anaphylaxis can occur without skin or airway manifestations, consistent with World Allergy Organization (WAO) criteria. Prompt recognition and early epinephrine administration are crucial to improving patient outcomes
Co-Authors Sukmono, Raden Besthadi