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All Journal Syntax Literate: Jurnal Ilmiah Indonesia Surabaya Biomedical Journal
Surya Atmaja, Kadek
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Humanities Dentistry Education Environmental Science Health Professions Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Social Sciences Other

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KARAKTERISTIK PENYAKIT KOMORBID PADA PASIEN INFEKSI COVID-19 Laksmi Dewi, Saraswati; Kartika Dewi, Ratna; Surya Atmaja, Kadek
Surabaya Biomedical Journal Vol. 5 No. 2 (2026): Januari
Publisher : Fakultas Kedokteran, Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/v5i2.178

Abstract

COVID-19 is an emerging global infection with a significant impact on people's lives.  This study aims to describe the characteristics of comorbidities in COVID-19-infected patients at Sanjiwani Teaching Hospital and Kasih Ibu Hospital in Denpasar. The research method used was a descriptive, cross-sectional observational study involving 115 adult patients diagnosed with COVID-19 based on RT-PCR test results. Demographic data, symptoms, laboratory results, and comorbidities were recorded. The results showed that the majority of patients were over 60 years old, with fever (78.3%) as the most common complaint. Laboratory results indicated moderate COVID-19 severity (52%) and severe-critical (47.8%). The most common comorbidities found were hypertension and diabetes mellitus. This study highlights the importance of monitoring and managing comorbidities to improve clinical outcomes for COVID-19 patients.
Pulmonary Complications as Predictors of Weaning Outcomes in Myasthenic Crisis: A Systematic Review and Meta-analysis Rossyana Dewi, Putri; Surya Atmaja, Kadek; Widyantara, I Wayan; Harry Pranata, I Made
Syntax Literate Jurnal Ilmiah Indonesia
Publisher : Syntax Corporation

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Abstract

Pulmonary complications are common during invasive mechanical ventilation in myasthenic crisis and may significantly influence extubation success. Although pneumonia, ventilator-associated pneumonia (VAP), and atelectasis are frequently reported, their quantitative association with weaning outcomes has not been systematically evaluated. The research aims to determine whether pneumonia/VAP and atelectasis are associated with poor weaning outcomes—including extubation failure, prolonged mechanical ventilation, or difficult weaning—in patients with myasthenic crisis. This systematic review and meta-analysis followed PRISMA 2020 guidelines and was registered in PROSPERO. Comprehensive searches of MEDLINE, Embase, Scopus, and CENTRAL were conducted through January 2025. Observational studies in adult myasthenic crisis were included. Risk ratios (RRs) were pooled using a random-effects model; risk of bias was assessed with ROBINS-I, and evidence certainty with GRADE. Of 1,246 records, 934 were screened after deduplication; 60 full-texts assessed; 4 studies included. Pneumonia/VAP was significantly associated with poor weaning outcomes (RR = 1.78, 95% CI 1.41–2.24; = 3%). Atelectasis showed a nonsignificant trend (RR = 1.28, 95% CI 0.93–1.75; = 35%). Evidence certainty was moderate for pneumonia/VAP and low for atelectasis. Publication bias was unassessable due to few studies. Pneumonia and VAP substantially increase extubation failure and weaning difficulties in myasthenic crisis. Atelectasis's role remains inconclusive. Aggressive pulmonary infection management may improve outcomes; prospective studies are needed
Co-Authors Harry Pranata, I Made I WAYAN WIDYANTARA Kartika Dewi, Ratna Laksmi Dewi, Saraswati Putri Rossyana Dewi