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Singh, Surjit
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Hubungan Kadar Kolesterol Total Dengan Kolesterol LDL Pada Pasien Hipertensi So Hanggrainy, Octavia; Lim, Hadyanto; Singh, Surjit
Jurnal Kedokteran Methodist Vol. 17 No. 1 (2024): Jurnal Kedokteran Methodist
Publisher : Universitas Methodist Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46880/jkm.v17i1.1392

Abstract

The Background: Cholesterol is an essential structural component that forms the cell membrane and the external layer of plasma lipoproteins. The increase of total cholesterol is always accompanied by the increase in LDL cholesterol especially in hypertensive patients. The present study was conducted to find the correlation between total cholesterol and LDL cholesterol of the patients with hypertension Method: It is an observational analytic using cross sectional study in which the data were collected by clinical laboratory examination of Prodia Jl. S.Parman no. 17/223G Medan, North Sumatra Indonesia. The population included all patients with hypertension in which the samples were taken by consecutive sampling method so the total were 19 samples. Results: Majority of samples had normal total cholesterol of 8 persons (42.1%) and the majority of the study samples had high LDL cholesterol of 8 persons (42.1%). Conclusion: There is a significant correlation between total cholesterol and LDL cholesterol. It is indicated by the sig-p value = 0.004 (p <0.05). There is a significant correlation between total cholesterol and LDL cholesterol of the patients with hypertension. It is indicated by the correlation coefficient value r-count = 0.635 which is between 0.6 - 0.79
Hubungan Hipertensi Dengan Mikroalbumin Urin Pada Usia Diatas 40 Tahun Cristianto Sagala, Rudy; Lim, Hadyanto; Singh, Surjit
Jurnal Kedokteran Methodist Vol. 17 No. 1 (2024): Jurnal Kedokteran Methodist
Publisher : Universitas Methodist Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46880/jkm.v17i1.1410

Abstract

Background : Hypertension is the risk factor for cardiovascular disease and it is related with endothelial dysfunction. The disease is marked by microalbuminuria. Microalbuminuria is related with the damage of endothelial glomerulus and predictor of chronic renal failure. Microalbuminuria increases albuminuria. This will manifest as endothelial damage of the glomerulus. This study is to assess the relation between hypertension and microalbuminuria in people over 40 years of age Methods : in 13 subjects of essential hypertension in Medan, basic data down and their blood pressure and microalbumin checked in Clinical Laboratory of Prodia on Jl. S. Parman No. 17/223 G Medan. This research use cross section study. Shapiro-Wilk test conducted to find out normal distribution data and Pearson correlation test conducted to find out the relation between the variables. The significant score is P<0.05. Results : 6 subjects in this research were in category of A2 (moderate): 3-30 mg/mmol creatinine.7 subject in this study were in category A3(Severe): >30 mg/mmol creatinine. There was correlation (r = 0.898, p = 0.000) between systolic hypertension and microalbuminuria and the correlation between diastolic and microalbuminuria was (r = 0.574, p = 0.040). Conclusion: Hypertension is related with the increase of microalbuminuria for both systolic hypertension and diastolic Hypertension.
Co-Authors Cristianto Sagala, Rudy Hadyanto Lim So Hanggrainy, Octavia