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All Journal Journal of Pharmaceutical and Sciences. Jurnal Etnofarmasi
Nadziatul Khasanah
UNIVERSITAS PENDIDIKAN MUHAMMADIYAH SORONG
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health

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PERBANDINGAN METODE EKSTRAKSI TERHADAP KADAR TOTAL FLAVONOID DAN ALKALOID DAUN BATIK PAPUA (Graptophyllum pictum L. griff) Nadziatul Khasanah; A.M. Muslihin
JURNAL ETNOFARMASI Vol. 3 No. 01 (2025): JURNAL ETNOFARMASI
Publisher : Universitas Pendidikan Muhammadiyah Sorong

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36232/jurnalfarmasiunimuda.v3i01.1964

Abstract

One of the plants used as medicine by the community is the Papuan batik leaf (Graptophyllum pictum L. Griff). Empirically, this leaf is used to treat anemia, treat wounds, liver swelling, gallstones, and treat coughs. This study aims to determine the results of the extract yield based on differences in cold extraction methods (maceration) and hot methods (soxhletation and reflux) and to identify functional groups contained in plants using the FTIR spectroscopy method and to see differences in total alkaloid and flavonoid compound levels based on differences in extraction methods using the UV-Vis spectrophotometry method. The results of the research that has been carried out indicate that there is the most effective extraction method used, namely the soxhletation method with an extract weight of 14 g and a yield percentage of 28%. Phytochemical screening test of Papua batik leaf ethanol extract using maceration, soxhletation, and reflux methods proved to contain alkaloid, flavonoid, tannin, terpenoid, and steroid compounds, also proven by the results of FTIR test with the presence of N-H, C=C, C-H, C-N, and C-O functional groups in the extract. The highest flavonoid content in the maceration method was 322.414 mg/g extract and the highest alkaloid content in the maceration method was 144.6 mg/g extract.
Evaluasi Mutu Fisikokimia dan Aktivitas Antioksidan Minuman Isotonik Ekstrak Batang Tali Kuning (Anamirta cocculus (L.) Wight & Arn.) Nadziatul Khasanah; A.M. Muslihin; Marzella Dea Rossardy; Justitia Cahyani Fadli
Journal of Pharmaceutical and Sciences JPS Volume 9 Nomor 2 (2026)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v9i2.1529

Abstract

as having potential as a natural antioxidant agent. One potential way to utilize this plant is by innovating it into an isotonic drink product. Objective: This study aimed to evaluate the physicochemical properties and antioxidant activity of an isotonic drink formulated with yellow rope stem extract. Methods: he extraction process was conducted using the maceration method with 70% ethanol as the solvent. The isotonic drink was developed into three formulas, which were then tested for their physicochemical properties and antioxidant activity using the DPPH method. Results: The results indicated that the best formula was FII, with an overall hedonic score of 4,6 (neutral). All three formulas showed identical pH values (4,0) and Total Soluble Solids (TSS) of 7%, while the total acidity decreased progressively: FI (1,024%), FII (0,896%), and FIII (0,704%). The isotonic drinks from yellow rope stem extract for formulas FI, FII, and FIII produced IC50 values of 35,61, 46,56, and 57,69 μg/mL, respectively. Based on these data, FI and FII were identified as having very strong antioxidant intensity, while the FIII showed activity classified in the strong category. Conclusion:.The test results demonstrate that the isotonic drink made from yellow rope stem extract exhibits antioxidant potential with intensity levels ranging from strong to very strong.
Co-Authors A. M. Muslihin Justitia Cahyani Fadli Marzella Dea Rossardy