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All Journal Sciences of Pharmacy Kolaborasi Masyarakat
Anggraeni, Indiana Gita
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Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Education Health Professions Languange, Linguistic, Communication & Media Medicine & Pharmacology Public Health Social Sciences

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Peningkatan Pengetahuan Masyarakat tentang Pengelolaan Obat melalui Edukasi DAGUSIBU dan Beyond Use Date di Posyandu Jeruk, Kota Semarang Anggraeni, Indiana Gita; Maharyani, Airina; Aunila, Faiqotut Tahta; Avivah, Ainaya Wahyu Cahyaning; Pradana, Della Wahyu; Nafiha, Ahmad Mizan; Istiqhfarin, Hilda Amie Shafira

Publisher : ETFLIN

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Abstract

Irrational use of medicines poses significant health risks, particularly in communities with limited access to pharmaceutical information. This study aimed to evaluate short-term changes in knowledge following education on DAGUSIBU (Get, Use, Store, and Dispose of Medicines Properly) and Beyond Use Date (BUD) among mothers attending Posyandu Jeruk, Semarang. The activity employed a pre–post evaluative design without a control group and involved 20 participants. Knowledge levels were assessed using a structured questionnaire administered before and immediately after the educational session. Data were analyzed using the Wilcoxon signed-rank test. The mean knowledge score increased from 5.75 to 7.40 (p = 0.001), indicating a statistically significant short-term improvement in knowledge. These findings suggest that DAGUSIBU and BUD education was associated with an immediate increase in participant knowledge; however, causal relationships and long-term impacts cannot be inferred from this study.
GC-MS Profiling and Literature-Based Mechanistic Prediction of Lemon Essential Oil and Mango Leaf Extract as Potential Supportive Candidates for Nicotine Addiction Management Sulistiyaningsih, Sulistiyaningsih; Rini, Tri Diana Puspita; Anggraeni, Indiana Gita
Sciences of Pharmacy Volume 5 Issue 2 (2026)
Publisher : ETFLIN

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58920/sciphar0502665

Abstract

Nicotine addiction remains a major global health problem that necessitates the development of safe and effective supportive therapies. This study aimed to characterize the metabolite profiles of lemon essential oil (Citrus limon (L.) Burm. f.) and 96% ethanol extract of mango leaves (Mangifera indica L.) using Gas Chromatography–Mass Spectrometry (GC-MS) and to explore their potential mechanisms in nicotine addiction management through a literature-based mechanism mapping approach. Compounds were identified based on retention time, mass spectrum matching, and relative peak area percentages. GC-MS analysis showed that lemon essential oil was predominantly composed of D-limonene (58.72%), followed by β-pinene (13.82%) and γ-terpinene (11.43%). Meanwhile, the 96% ethanol extract of mango leaves was dominated by methyl gallate (27.61%), along with several phenolic compounds and triterpenoids, including vitamin E and lupeol. The identified metabolites suggest distinct but potentially complementary biological activities. Lemon essential oil may exert supportive effects through neuromodulatory pathways, whereas mango leaf extract may contribute through antioxidant and anti-inflammatory mechanisms. These findings indicate that both natural products possess potential complementary roles as supportive agents in nicotine addiction management. However, further biological and clinical studies are required to validate their efficacy and safety.
Co-Authors Aunila, Faiqotut Tahta Avivah, Ainaya Wahyu Cahyaning Istiqhfarin, Hilda Amie Shafira Maharyani, Airina Nafiha, Ahmad Mizan Pradana, Della Wahyu Sulistiyaningsih Sulistiyaningsih Tri Diana Puspita Rini