Wulansari, Devyani Diah
Laboratorium Farmasi Klinis Dan Komunitas, Fakultas Farmasi, Universitas Surabaya

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EFEK PAPARAN KRONIS PESTISIDA TERHADAP KADAR ASPARTAT AMINOTRANSFERASE (AST) DAN ALANIN AMINOTRANSFERASE (ALT) PADA SUBYEK PETANI Devyana Dyah Wulandari; Andreas Putro Ragil Santoso; Devyani Diah Wulansari
THE JOURNAL OF MUHAMMADIYAH MEDICAL LABORATORY TECHNOLOGIST Vol 3, No 2 (2020): The Journal of Muhammadiyah Medical Laboratory Technologist
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jmlt.v3i2.5853

Abstract

Farmers in Indonesia are very dependent on pesticides to protect their crops from pests. Farmers are one of the subjects who are susceptible to pesticides and can cause disease due to pesticide accumulation. One of the disease that can arise due to exposure to pesticides is liver damage. This study wanted to determine the effect of pesticide exposure on liver damage seen from AST and ALT enzyme levels using farmer respondents in the Mojokerto area of 25 respondents. From the results of the study it was found that AST levels were influenced by age (P = 0.017), length of work (P = 0.035), and PPE usage (P = 0.044), while age, work period, length of work and usage of PPE did not significantly influence to ALT levels. It can be concluded that age, length of work and use of PPE affect AST levels. Therefore, to prevent the occurrence of pesticide poisoning, farmers must obey the rules on the use of pesticides such as using PPE regularly and always consuming healthy food.
Pengembangan Model Hewan Coba Tikus Diabetes Mellitus Tipe 2 dengan Induksi Diet Tinggi Fruktosa Intragastrik Devyani Diah Wulansari; Devyana Dyah Wulandari
MPI (Media Pharmaceutica Indonesiana) Vol. 2 No. 1 (2018): JUNE
Publisher : Fakultas Farmasi, Universitas Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (545.459 KB) | DOI: 10.24123/mpi.v2i1.1302

Abstract

Pada beberapa tahun terakhir banyak dikembangkan model hewan diabetes mellitus untukmemahami patogenesis, komplikasi, dan pengaruh genetik yang meningkatkan risiko diabetes mellitustipe 2, baik dengan menggunakan bahan kimia maupun dengan modifikasi secara genetik termasuk tikusknockout transgenik, umum, dan knockout spesifik jaringan. Dalam penelitian ini model hewan diabetesmellitus tipe 2 dikembangkan melalui metode pendekatan konsumsi gula pada manusia dengan mengacupada karakteristik kondisi diabetes mellitus tipe 2, penyebab atau mekanisme yang mendasari, serta pertimbangankeuntungan dan kerugian bagi para peneliti dalam penelitian diabetes. Penelitian ini menggunakan32 ekor hewan coba, diadaptasikan selama 14 hari kemudian dibagi dalam 4 kelompok yaitukelompok kontrol, kelompok perlakuan yang diberi larutan fruktosa 2, 5, dan 9 g/kgBB selama 56 hari.Hasil uji komparasi menunjukkan bahwa terdapat perbedaan bermakna antar kelompok (p<0,05) padavariabel dosis fruktosa dan gula darah puasa akhir. Dari penelitian ini dapat disimpulkan bahwa pemberianfruktosa secara intragastrik jangka panjang dapat memicu kenaikan glukosa darah puasa pada tikus.
Peningkatan Keterampilan dan Produktivitas Ekonomis Panti Asuhan Grha Aitam Al Madina Devyani Diah Wulansari; Emma Savitri; Hayuning Purnama Dewi
CARADDE: Jurnal Pengabdian Kepada Masyarakat Vol. 4 No. 2 (2021): Desember
Publisher : Ilin Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31960/caradde.v4i2.1334

Abstract

The purpose of this service program is to improve skills and productivity. economical partner. The method used is through mentoring and training programs by academics from the University of Surabaya related to halal certification, analysis of honey content for quality control and improvement of the packaging process to improve the hygiene of honey products. From the results of this community service program, Partners succeeded in obtaining LPPOM MUI halal certificates for Honey products, analysis of water content, metals, ash, microbial contamination, diastase enzymes, and Hydroxymethyl Furfural (HMF) by SNI 8664-2018, and the honey packaging process through the application of appropriate technology to maintain the hygiene and quality of honey.