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All Journal Biology, Medicine, & Natural Product Chemistry Arfak Chem: Chemistry Education Journal
Boima Situmeang
Sekolah Tinggi Analis Kimia Cilegon, Banten
Humanities Biochemistry, Genetics & Molecular Biology Chemistry Education Medicine & Pharmacology Public Health Social Sciences

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Antioxidant and Antibacterial Properties of Methanol Extract of Gletang Flower (Tridax procumbens) Boima Situmeang; Weny JA Musa; Nurhayati Bialangi; Sriwijayanti Sriwijayanti; Holisha Widiyanto; Dian Susvira
Biology, Medicine, & Natural Product Chemistry Vol 14, No 2 (2025)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/biomedich.2025.142.1085-1090

Abstract

In a previous study, the methanol extract of Tridax procumbens flowers (commonly known as gletang) at high concentrations was reported to exhibit strong antibacterial activity against Streptococcus mutans and Enterococcus faecalis. This study aimed to examine the secondary metabolite content, antioxidant activity, and antibacterial activity of the methanol extract of gletang flowers. The antioxidant activity was evaluated using two methods, namely DPPH and ABTS assays. The antibacterial activity was assessed using the Kirby-Bauer method at concentrations of 1000, 5000, and 10000 ppm against Staphylococcus aureus, Escherichia coli, Streptococcus mutans, and Enterococcus faecalis. Phytochemical screening revealed that the methanol extract of gletang flowers contains phenolic compounds, flavonoids, alkaloids, and triterpenoids. The antioxidant activity tests showed very strong activity in both DPPH and ABTS assays, with IC50 values of 6.8478 ± 1.335 and 12.8608 ± 0.579 ppm, respectively. The antibacterial activity tests showed that the methanol extract of gletang flowers exhibited strong activity against E. faecalis at concentrations of 5000 and 10000 ppm, with inhibition zone diameters of 3.00 ± 0.14 and 3.20 ± 0.14 mm, respectively.
Comparison of the Antioxidant Activity of n-Hexane Extract of Gandaria Stem Bark Using DPPH and ABTS Assays Agus Malik Ibrahim; Dina Alva Prastiwi; Boima Situmeang
Arfak Chem: Chemistry Education Journal Vol. 9 No. 1 (2026): Arfak Chem
Publisher : Universitas Papua, Manokwari, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30862/accej.v9i1.1268

Abstract

This study aimed to evaluate and compare the antioxidant activity of the n-hexane extract of gandaria (Bouea macrophylla) stem bark using DPPH and ABTS methods. This research was conducted as a laboratory-based quantitative study. The extraction was performed using the maceration method with n-hexane as a solvent, yielding 6.2% extract. Antioxidant activity was determined from IC₅₀ values obtained by linear regression of concentration versus percentage inhibition. The results showed that the n-hexane extract exhibited strong antioxidant activity, with IC₅₀ values of 26.695 ± 0.892 ppm for the DPPH method and 17.28 ± 0.352 ppm for the ABTS method. The lower IC₅₀ value obtained in the ABTS assay indicates a higher radical-scavenging capacity than in the DPPH assay. These differences are likely due to variations in radical types and reaction mechanisms between the two assays. In conclusion, the n-hexane extract of Gandaria stem bark demonstrates strong antioxidant potential. The ABTS method showed greater sensitivity than the DPPH method in evaluating antioxidant activity. These findings suggest that Gandaria stem bark has potential as a natural antioxidant source, and further research is required to elucidate its active constituents.
Co-Authors Agus Malik Ibrahim Dian Susvira Dina Alva Prastiwi Holisha Widiyanto Nurhayati Bialangi Sriwijayanti Sriwijayanti