Claim Missing Document
Check
Articles

Found 3 Documents
Search

Ethnic Variability in the Perception of Postoperative Pain In Jos, Plateau State, Nigeria Usman Y. M; Shugaba A. I; Zoakah A. I
African Multidisciplinary Journal of Sciences and Artificial Intelligence Vol 1 No 2 (2024): African Multidisciplinary Journal of Sciences and Artificial Intelligence
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/amjsai.v1i2.3926

Abstract

Background: Postoperative pain management is crucial to patient care and recovery after surgery. Effective pain control not only alleviates suffering but also facilitates quicker recovery, reducing the risk of complications such as chronic pain syndromes. By identifying ethnic differences in pain perception, healthcare providers can tailor their pain management strategies better to meet the needs of patients from diverse cultural backgrounds. This study therefore sought to determine and compare baseline and serial postoperative pain scores using a visual analogue scale among non-indigenous (Fulani, Hausa, Igbo, and Yoruba) and Indigenous ethnic groups (Berom, Tarok, Ngas, and Mwagavul) in Plateau State, Nigeria. Materials and Methods: This was a comparative cross-sectional study conducted among 88 adults of Indigenous and non-indigenous ethnic groups of Plateau State at the Jos University Teaching Hospital (JUTH) recruited through stratified random sampling. The equal proportion allocation technique was employed for gender and ethnic groups. Ethical clearance, informed verbal and written consent were obtained before the commencement of the study. Baseline pain scores were determined by a pressure algometer. A pressure of 20N was applied bilaterally on the trapezius muscle between the C7 spinous process and the acromial process, and then the subjects were asked to rate the pain they felt on a numeric rating scale (NRS). The average NRS score was taken as the baseline pain score. Serial 2-hourly postoperative pain scores were also assessed in the immediate 24-hour postoperative period. All analyses were conducted using Statistical Package for Social Sciences version 23 (SPSS Inc., Chicago, IL, USA). Significance was set at the α = 0.05 level. Results: A total of 88 patients participated in this study with an equal number of gender and ethnic group representation. The median (IQR) age of study participants was 21 (19.2–35.6) years. No significant statistical difference in median baseline pain scores between the entire indigenous (21.5) and non-indigenous (21.0) ethnic groups, U = 0.64, p = 0.22. There was a statistically significant difference in baseline median pain scores between females (3.5) and males (2.0), U = 3.0, p = 0.036 in the indigenous and females (3.0) and males (2.0) in the non-indigenous ethnic groups, U = 3.9, p = 0.013. This study revealed a statistically significant difference in the median serial postoperative pain scores in the different specific Indigenous ethnic groups (H (2) = 24.2, p = 0.001) and the different specific non-indigenous ethnic groups (H (2) = 24.8, p = 0.001) as well. Conclusion: This study has demonstrated ethnic and gender variability in the perception of pressure and postoperative pain among different ethnic groups resident in Plateau State. Clinicians need to be aware of the fact that different ethnic groups in Plateau State perceive pain differently and put it into consideration when treating pain.
Mitigating Alcohol-Induced Liver Enzyme Alterations in Wistar Rats Through Forced Swimming Exercise Abdul-Kareem Y. I; Chidiebere U; Yilgwan G; Usman Y. M; Galam N. Z
African Journal of Biochemistry and Molecular Biology Research Vol 1 No 1 (2024): African Journal of Biochemistry and Molecular Biology Research
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajbmbr.v1i1.3703

Abstract

This study investigates the impact of forced swimming exercise on alcohol-induced alterations in hepatic enzyme biomarkers in Wistar rats (mean weight 150-200g). Twenty Wistar rats were randomly divided into four groups of five rats each: a normal control group, an exercise-only group, an alcohol-only group, and an exercise plus alcohol group. The control group received 0.9% normal saline 5 days a week for 12 weeks. The exercise group underwent forced swimming for 5 minutes a day, 5 days a week, for 12 weeks. The alcohol group received 20% ethanol orally at a dose of 2.0g/kg body weight. The combined exercise and alcohol group followed the same protocols as the exercise and alcohol groups. At the end of the 12-week period, all animals were euthanized, and blood samples were collected for analysis of hepatic enzyme biomarkers, including ALT, AST, and GGT, using an automated serum biochemistry analyzer. Results showed significant elevation of hepatic enzyme biomarkers in the alcohol-only group, while the normal control, exercise-only, and exercise plus alcohol groups exhibited decreased enzyme levels. These findings indicate that exercise mitigates alcohol-induced liver enzyme alterations in adult male Wistar rats. The study suggests that exercise training may be effective in alleviating liver damage from chronic alcohol consumption and could potentially prevent liver failure and hepatocellular carcinoma.
Duration of Analgesic Free Period and Haemodynamic Stability Following Paediatric Herniotomy: A Comparison of Caudal Block Versus Pre-Incisional Field Block with Diclofenac Suppository Kpalap P. B; Usman Y. M; Aliyu H. A; Shaki R; Malau K. T; Nuhu S. I; Embu H. Y; Isamade E. S
African Journal of Medicine, Surgery and Public Health Research Vol 2 No 1 (2025): African Journal of Medicine, Surgery and Public Health Research
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajmsphr.v2i1.4242

Abstract

Paediatric herniotomy, a common surgical procedure in children, demands effective perioperative pain management to ensure patient comfort and minimise complications. Optimal pain control is crucial in paediatric populations due to their heightened sensitivity to pain and the potential long-term impact of poorly managed acute pain on their neurodevelopment. The choice between caudal block and field block with diclofenac remains a subject of debate. Factors such as the duration of analgesic-free periods and haemodynamic stability need to be assessed to guide clinical decisions. This study was conducted in the Jos University Teaching Hospital, Jos, Nigeria, among paediatric patients presenting for inguinal herniotomy. We conducted a randomised, single-blind controlled clinical trial where patients were recruited through the purposive sampling technique. Inclusion criteria included elective day cases, open unilateral inguinal herniotomies, and children aged 1–6 years with ASA physical classes I and II. One group of patients received 1 mL/kg of 0.25% plain bupivacaine caudally, while the other group of patients received pre-incisional field block with 1 mL/kg of 0.25% plain bupivacaine and diclofenac suppository 1 mL/kg. duration of analgesic-free period and intraoperative haemodynamic parameters were assessed and documented. All the 58 enrolled patients were included in the final analysis, having completed the study. The study groups were comparable in all measured patient characteristics. The duration of analgesic free period was shorter in the caudal block group compared with the field block with diclofenac suppository group (282.86±18.43 minutes in the caudal block group and 291.03±16.33 minutes in the field block with diclofenac suppository group, p = 0.155). The heart rates, systolic blood pressures, diastolic blood pressures, and mean arterial pressures across both study groups were comparable from the start of surgery to the end of surgery. It can be concluded that both caudal block with 1 mL/kg of 0.25% plain bupivacaine and pre-incisional field block with 1 mL/kg of 0.25% plain bupivacaine plus 1 mL/kg of diclofenac suppository were comparable in providing effective post-herniotomy analgesia in the paediatric age group.