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Exploring the Dynamics of Enzyme Activity: Environmental and Biological Influences Muhammad Akram; Urooj Rehman; Misbah Ahmed; Isaac John Umaru
African Journal of Biochemistry and Molecular Biology Research Vol 2 No 2 (2025): African Journal of Biochemistry and Molecular Biology Research
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajbmbr.v2i2.5268

Abstract

The work presents the classification of enzymes and factors that are affecting enzymatic reactions in the living systems. Factors such as temperature, pH, enzyme concentration, substrate concentration, factors of inhibition, factors of activation, and incubation time are important in influencing enzyme reactions, which are responsible for controlling components in living systems. The majority of enzymes are three-dimensional molecules with complex molecular networks and sensitive to various environmental factors.
Phytochemistry and Pharmacology of Oxystelma Esculentum Abdul Wadood Chishti; Muhammad Akram; Urooj Rehman; Fahad Said Khan; Momina Iftikhar; Isaac John Umaru
African Journal of Biochemistry and Molecular Biology Research Vol 2 No 2 (2025): African Journal of Biochemistry and Molecular Biology Research
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajbmbr.v2i2.5269

Abstract

Several phytochemicals, including glycosides, alkaloids, flavonoids, and saponins, are present in the widespread medicinal herb Oxystelmaesculentum. These physiologically active substances contribute to the herb's pharmacological properties, which include anti-inflammatory, antioxidant, antibacterial, and antidiabetic effects. Research studies have shown that O. esculentum can be used medicinally to treat a variety of ailments, such as fever, pain, respiratory issues, and digestive issues. It may also have neuroprotective properties and help in blood sugar regulation. Even though its therapeutic qualities appear promising, more research must be done to verify its efficacy, safety, and potential for drug development.
Phytochemistry and Pharmacology of Trachyspermum ammi Muhammad Akram; Urooj Rehman; Misbah Ahmed
African Journal of Sciences and Traditional Medicine Vol 2 No 2 (2025): African Journal of Sciences and Traditional Medicine
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajstm.v2i2.5280

Abstract

Trachyspermum ammi is a member of the family Apiaceae. The majority of medical uses for seeds and roots are as spices and diuretics, respectively. Ajwain oil, a dark oil, is found in seeds. This oil is used to treat respiratory conditions, gastrointestinal problems, and hunger disorders. The oil exhibited antibacterial, antifungal, and anti-aggregatory properties. On the other hand, ajwain is a traditional potential herb that is used for a number of ailments. The fruit possesses carminative, antispasmodic, stimulant, and anti-diarrheal properties.
The Advancements and Future of Regenerative Medicine Muhammad Akram; Urooj Rehman; Isaac John Umaru
African Journal of Clinical Medicine and Pharmacy Research Vol 2 No 2 (2025): African Journal of Clinical Medicine and Pharmacy Research
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajcmpr.v2i2.5330

Abstract

The sector of healthcare is witnessing new advancements in the field of Regenerative Medicine as it aims to provide treatment options for previously considered unsolvable cases. Scientists are seeking ways through stem cell therapy, gene editing, and tissue engineering to restore or replace damaged tissues and organs. Stem cell therapy is a key player by creating tissues from non specialized cells. Tissue engineering and amplification of 3D bioprinting biomaterials allow the production of synthetic organs and therefore lessen the demand for actual organ donors. The use of CRISPR-Cas9 as a gene editing tool opens new opportunities for treating genetic issues such as cystic fibrosis or sickle cell anemia. The main challenge lies in the enormous expenditure, bureaucracy, ethics, and program rejection difficulty. Although these things slow the expansion of the methods to clinics, further deeper studying gives hope for the medicine to fully change the paradigm caring more about curing than relieving symptoms. The funds and innovations that go into regenerative therapies may prove one day to be the answer to millions globally.