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All Journal Proceeding Mulawarman International Conference on Tropical Public Health
Faris Regi Riswana
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Public Health

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Effect of Camellia sinensis on Hormones and Body Weight in PCOS: A Systematic Review and Meta-Analysis Zelin Patarena Dawi Pramesti; Safira Mauliyatul Chusna; Faris Regi Riswana; Noza Loviana
Mulawarman International Conference on Tropical Public Health Vol. 2 No. 2 (2025): The 4th MICTOPH
Publisher : Faculty of Public Health Mulawarman University, Indonesia

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Background: Polycystic Ovary Syndrome (PCOS) is the most common polygenic endocrine disorder in women of reproductive age. PCOS is characterized by symptoms of excess androgen hormones, ovulation disorders, and obesity. The polyphenol content in Camellia sinensis extract has been reported to be beneficial in lowering testosterone levels and stabilizing luteinizing hormone production, thereby improving the ovulation process in PCOS patients. Objective : Identify studies that use clinical trials and studies that evaluate Camellia sinensis extract in animal models of PCOS Research Methods/ Implementation Methods : A comprehensive search was conducted on five databases, including SCOPUS, Science Direct, PubMed, ProQuest, and EBSCO, published from 2015-2025 met inclusion criteria. Risk of bias was assessed using SYRCLE’s. Data were analyzed using RevMan 5.4 software Results: Three studies were included in the meta-analysis, which involved 74 female rats. Compared to the untreated PCOS rat group, managing of Camellia sinensis polyphenols to PCOS rats had a significant effect in reducing testosterone levels (MD = -7.17, 95% CI: -9.96 to -4.39, P < 0.00001, I² = 59%), luteinizing hormone (LH) levels (MD = -4.57, 95% CI: -4.67 to -4.46, P < 0.00001, I² = 15%), and body weight (MD = -40.31, 95% CI: -50.62 to -30.00, P < 0.00001, I² = 0%) indicating high consistency of treatment effects across all included studies. Conclusion/Lesson Learned : Camellia sinensis polyphenols significantly reduced testosterone, LH, and body weight levels in PCOS mouse models, demonstrating their potential as an effective alternative therapy for polycystic ovary syndrome management.
ACCURACY OF VISUAL INSPECTION WITH ACETIC ACID FOR CERVICAL LESIONS: A SYSTEMATIC REVIEW AND METAANALYSIS  Faris Regi Riswana; Faris Rega Riswana; Krisjentha Iffah Agustasari; Nabila Khairunisa Azzahra; Amanda Fransisca Rhevytasari
Mulawarman International Conference on Tropical Public Health Vol. 2 No. 2 (2025): The 4th MICTOPH
Publisher : Faculty of Public Health Mulawarman University, Indonesia

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Visual inspection with acetic acid (VIA) remains widely used for cervical cancer screening in low- and middle-income countries, despite ongoing concerns regarding its diagnostic accuracy. This study aimed to evaluate the diagnostic performance of VIA for detecting high-grade cervical lesions (CIN2+) compared with histopathology. A systematic search was conducted in PubMed, Scopus, and ScienceDirect (2015–October 2025). Eligible studies provided sufficient data to construct 2×2 tables and were assessed using QUADAS-2. A bivariate random-effects model and HSROC analysis were applied. Thirteen studies were included, with five eligible for quantitative synthesis. Sensitivity ranged from 0.25 to 0.92 and specificity from 0.49 to 0.97, indicating substantial heterogeneity. Risk of bias was generally low to moderate, mainly in patient selection and flow and timing domains. VIA demonstrates moderate accuracy with variability across populations. Although less sensitive than HPV-based screening, VIA remains a pragmatic option in resource-limited settings, particularly within screen-and-treat strategies, with strengthened training and quality assurance required
Co-Authors Amanda Fransisca Rhevytasari Faris Rega Riswana Krisjentha Iffah Agustasari Nabila Khairunisa Azzahra Noza Loviana Safira Mauliyatul Chusna Zelin Patarena Dawi Pramesti