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p-Index From 2021 - 2026
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All Journal Journal of Selvicoltura Asean Journal of Biomedical and Techno Nanomaterials
Ahmed Mohamed
University of Comoros
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology

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THE ROLE OF URBAN GREEN SPACES IN CLIMATE ADAPTATION OF SOUTHEAST ASIAN TROPICAL CITIES Ahmed Mohamed; Fatima Ibrahim; Amina Said
Journal of Selvicoltura Asean Vol. 3 No. 1 (2026)
Publisher : Yayasan Adra Karima Hubbi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70177/jsa.v3i1.3543

Abstract

Rapid urbanization in Southeast Asian tropical cities has intensified vulnerability to climate-related hazards, including urban heat islands, flooding, and reduced air quality. Limited green infrastructure exacerbates these challenges, while urban green spaces such as parks, gardens, and tree-lined streets offer potential mitigation by enhancing microclimate regulation, stormwater management, and social well-being. Despite recognition of their importance, the role of urban green spaces in climate adaptation remains insufficiently quantified and integrated into city planning. This study aims to evaluate the effectiveness of urban green spaces in supporting climate adaptation strategies in Southeast Asian tropical cities. The research focuses on their ecological, social, and infrastructural contributions to reducing urban vulnerability and enhancing resilience to climate stressors. A mixed-methods approach was employed, combining geospatial analysis of land cover and green space distribution, secondary climate and socio-economic data, and surveys of 300 residents across three major cities. Quantitative data were analyzed using statistical modeling to examine relationships between green space coverage and urban climate indicators, while qualitative data provided insights into community perceptions and adaptive practices. Results indicate that increased green space coverage correlates with reduced surface temperatures, improved stormwater absorption, and enhanced community awareness of climate risks. Residents reported higher well-being and perceived safety in areas with accessible green infrastructure. The study concludes that urban green spaces are essential components of climate adaptation strategies in tropical cities, offering co-benefits for ecology, social resilience, and infrastructure planning.
TARGETING THE TUMOR MICRO-ENVIRONMENT: NANOPARTICLE-MEDIATED DELIVERY OF IMMUNOMODULATORY DRUGS TO ENHANCE CANCER IMMUNOTHERAPY Omar Ali; Ahmed Mohamed; Mariam Hassan
Journal of Biomedical and Techno Nanomaterials Vol. 2 No. 6 (2025)
Publisher : Yayasan Adra Karima Hubbi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70177/jbtn.v2i6.2982

Abstract

The tumor micro-environment plays a central role in regulating antitumor immune responses and represents a major barrier to the effectiveness of cancer immunotherapy. Immunosuppressive cellular components, abnormal vasculature, and inhibitory cytokine networks often limit immune cell infiltration and reduce the efficacy of systemically administered immunomodulatory drugs. This study aims to investigate nanoparticle-mediated delivery strategies to selectively target the tumor micro-environment and enhance cancer immunotherapy outcomes. An experimental nanomedicine approach was employed, involving the design and characterization of drug-loaded nanoparticles, evaluation of biodistribution and tumor localization, and assessment of immunological responses in tumor models. Nanoparticle performance was compared with free drug administration to determine delivery efficiency and therapeutic impact. The results demonstrate that nanoparticle-mediated delivery significantly improved accumulation of immunomodulatory drugs within tumor tissues, leading to enhanced cytotoxic T cell infiltration, reduced immunosuppressive cell populations, and improved antitumor efficacy. Targeted delivery also reduced off-target immune activation and systemic toxicity compared to conventional administration. In conclusion, nanoparticle-based targeting of the tumor micro-environment offers an effective strategy to overcome immunosuppressive barriers and amplify the therapeutic potential of cancer immunotherapy. This approach provides a promising framework for the development of next-generation precision immuno-oncology treatments.
Co-Authors Amina Said Fatima Ibrahim Mariam Hassan Omar Ali