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All Journal Journal of Innovation Research and Knowledge Journal of Pharmascience
Reni Yustiati Saksono
RSUD Ulin Banjarmasin
Humanities Economics, Econometrics & Finance Education Health Professions Law, Crime, Criminology & Criminal Justice Social Sciences

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Antibiotic Use Patterns in Obstetric and Gynecological Surgery Patients: A Quantitative Descriptive Study Using ATC/DDD and DU90% Methods Maryamah Azzahra; Difa Intannia; Dita Ayulia Dwi Sandi; Reni Yustiati Saksono; Revina Aditya Yosita; Herningtyas Nautika Lingga
Journal of Pharmascience Vol. 13 No. 1 (2026): Jurnal Pharmascience
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v13i1.24199

Abstract

Surgical site infections (SSIs) are common postoperative complications in obstetric and gynecological surgery, with incidence rates up to 20% in cesarean sections. Antibiotics are the primary strategy for SSI prevention; however, antibiotic utilization patterns in this surgical setting remain poorly characterized locally. This study describes the antibiotic use profile, AWaRe classification, DDD/100 patient-days values, and DU90% segment among obstetric and gynecological surgery patients at Ulin Regional General Hospital, Banjarmasin, in 2024. A retrospective, non-experimental quantitative descriptive design was employed. Of 313 medical records reviewed, 137 met the inclusion criteria. A total of 173 antibiotic prescriptions were identified. Ceftriaxone was the most frequently used antibiotic (61.84%), with cephalosporins predominating (91.91%) and parenteral administration in 75.72% of cases. Based on the WHO AWaRe 2022 classification, 85.55% of antibiotics were in the Watch group and 13.29% in the Access group; no Reserve antibiotics were used. Ceftriaxone had the highest DDD/100 patient-days (33.74). Ceftriaxone and cefixime comprised the DU90% segment. These findings highlight a predominance of Watch-group antibiotics and support the need for targeted stewardship interventions
ANALISIS POTENSI TERJADINYA INTERAKSI OBAT PADA PENGOBATAN PASIEN DENGAN DIAGNOSA UTAMA PENYAKIT JANTUNG KORONER DI POLI JANTUNG RSUD ULIN BANJARMASIN Syifa Aprilia Nur Aini; Tuty Mulyani; Reni Yustiati Saksono
Journal of Innovation Research and Knowledge Vol. 6 No. 2 (2026): Juli 2026
Publisher : Bajang Institute

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Abstract

Abstrak: Penyakit Jantung Koroner (PJK) terjadi akibat penyumbatan atau penyempitan arteri koroner oleh proses aterosklerosis dan penumpukan lemak, yang menghambat aliran darah ke jantung. Interaksi obat merupakan salah satu faktor yang dapat memperburuk kondisi ini.Penelitian Ini bertujuan untuk mengetahui persentase potensi terjadinya interaksi obat pada pengobatan pasien dengan diagnosa utama PJK di poli jantung RSUD Ulin Banjarmasin meliputi potensi interaksi obat berdasarkan tingkat keparahan, dan obat yang paling sering berpotensi berinteraksi. Jenis Penelitian ini adalah penelitian analitik deskriptif yang dilakukan secara retrospektif dengan melihat data resep pasien dengan diagnosa utama PJK di poli jantung RSUD Ulin Banjarmasin bulan januari-desember 2023 dengan menggunakan teknik total sampling, dan dianalisis secara deskriptif dengan menggunakan Interactions Checker (Drugs.com). Berdasarkan analisis potensi interaksi obat yang telah dilakukan diketahui dari total 49 lembar resep pasien yang dianalisis, terdapat 38 lembar resep yang memiliki potensi interaksi obat dan dari 38 lembar resep tersebut didapat hasil total potensi interaksi obat sebanyak 119 potensi interaksi obat. Tingkat keparahan potensi interaksi obat paling banyak pada moderate sebanyak 73,95%, lalu minor sebanyak 19,33%, dan pada mayor sebanyak 6,72%. obat yang paling sering berinteraksi yaitu Atorvastatin+Clopidogrel sebanyak 21 kasus
Co-Authors Ayulia Dwi Sandi, Dita Difa Intannia Herningtyas Nautika Lingga Maryamah Azzahra Revina Aditya Yosita Syifa Aprilia Nur Aini Tuty Tuty Mulyani