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Analysis of Dengue Hemorrhagic Fever in Adult Patients in Panti Rahayu Yakkum Purwodadi Hospital Milga Mahargyaning Vianda Widodo; Endang Setyowati; Ulviani Yulia Husna
Advances in Healthcare Research Vol. 4 No. 1 (2026): September - February
Publisher : Yayasan Pendidikan Bukhari Dwi Muslim

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.60079/ahr.v4i1.706

Purpose: This study aimed to analyze the treatment of dengue hemorrhagic fever in adult inpatients at Panti Rahayu Yakkum Purwodadi Hospital and to evaluate the appropriateness of therapy based on the 2020 Indonesian Ministry of Health guideline. Research Method: This research used a non-experimental observational design with a retrospective descriptive-analytic approach. Data were collected from the medical records of 95 adult inpatients diagnosed with dengue hemorrhagic fever during January-September 2025 using purposive sampling. The variables included patient characteristics, supportive therapy, concomitant drugs, and therapeutic appropriateness. Data were analyzed descriptively and evaluatively. Results and Discussion: The most frequently used therapies were Ringer Lactate infusion (96.84%), paracetamol 500 mg (50.53%), and intravenous paracetamol (45.26%). Evaluation showed appropriate indication in 70.5% of cases, appropriate drug in 51.6%, appropriate patient in 93.7%, and appropriate dose in 95.8%. The findings indicate that dengue treatment was largely dominated by supportive therapy, although some inappropriate drug use was still identified. Implications: The findings underscore the importance of adherence to clinical guidelines for improving therapeutic safety and effectiveness. Further studies are recommended to examine the relationship between therapeutic appropriateness, clinical outcomes, complications, and length of hospitalization.

Evaluation of Antituberculosis Therapy In HIV/AIDS Patients at X Hospital Kudus Elsa Latifatul Luthfi; Endang Setyowati; Intan Adevia Rosnarita
Advances in Healthcare Research Vol. 4 No. 1 (2026): September - February
Publisher : Yayasan Pendidikan Bukhari Dwi Muslim

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.60079/ahr.v4i1.707

Purpose: This study aimed to evaluate the use of antituberculosis drugs (OAT) in HIV/AIDS patients with tuberculosis coinfection at X Hospital in Kudus by identifying patient characteristics, patterns of OAT and antiretroviral (ARV) use, and the rationality of OAT therapy using the Gyssens method. Research Method: This study used a descriptive evaluative design with a retrospective approach based on medical record data. The sample consisted of 41 HIV/AIDS patients with TB coinfection treated at X Hospital in Kudus during November 2024-November 2025, selected using total sampling. Data were analyzed univariately, while therapeutic rationality was assessed using the Gyssens method. Results and Discussion: Most patients were adults (92.7%) and male (82.9%). The most common OAT regimen was RHZE (4FDC) (70.7%), while the dominant ARV regimen was TLD (95.1%). All OATs were administered orally as tablets, and the duration of therapy was appropriate in all cases. The Gyssens evaluation showed rational OAT use in 95.1% of patients and irrational use in 4.9%, with inappropriate dosage as the main problem. Implications: These findings indicate that OAT prescribing practices were generally consistent with treatment guidelines, but body-weight-based dose adjustment still requires improvement. Further studies should explore the relationship between rational therapy, adherence, and clinical outcomes in TB-HIV patients.

Analysis of Patient Satisfaction Levels Toward the Implementation of Electronic Prescribing (E-Prescribing) in the Outpatient Department of Jekulo Kudus Community Health Center Ira Setia Lestari; Endang Setyowati; Intan Adevia Rosnarita
Advances in Healthcare Research Vol. 4 No. 1 (2026): September - February
Publisher : Yayasan Pendidikan Bukhari Dwi Muslim

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.60079/ahr.v4i1.713

Purpose: This study aimed to analyze patient satisfaction with the implementation of electronic prescribing (e-prescribing) in the outpatient department of Jekulo Kudus Community Health Center and to identify the relationship between patient satisfaction and respondent characteristics as well as service-related indicators. It was hypothesized that e-prescribing implementation was associated with a good level of patient satisfaction, although several service attributes still required improvement. Research Method: This study used an analytical observational method with a cross-sectional design involving 96 outpatients. Data were collected using a questionnaire based on five SERVQUAL dimensions: tangibles, reliability, responsiveness, assurance, and empathy. Data analysis included validity and reliability testing, univariate analysis, bivariate analysis using the Mann-Whitney test, and Importance Performance Analysis (IPA). Results and Discussion: Patient satisfaction was significantly associated with age, education level, health insurance status, and frequency of visits to the pharmacy clinic (p < 0.001), while gender, employment status, and number of medications received were not significantly related (p > 0.05). All SERVQUAL dimensions showed high perceived performance scores, indicating generally good satisfaction. However, IPA identified several priority areas for improvement, particularly the clarity of drug information, staff responsiveness, and patient attention. Implications: The findings indicate that e-prescribing has improved outpatient pharmaceutical services, but continuous efforts are needed to strengthen communication and patient-centered interaction. Further studies should explore system efficiency and long-term patient outcomes.

Medication Profile and Side Effect - Severity of Anti-Tuberculosis Drugs in Pulmonary Tuberculosis Patient at Bhina Bhakti Husada Rembang Hospital Nike Sri Wulandari; Endang Setyowati; Intan Adevia Rosnarita
Advances in Healthcare Research Vol. 4 No. 1 (2026): September - February
Publisher : Yayasan Pendidikan Bukhari Dwi Muslim

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.60079/ahr.v4i1.714

Purpose: This study aimed to identify the treatment profile and the type and severity of anti-tuberculosis drug (OAT) side effects in pulmonary tuberculosis patients at Bhina Bhakti Husada Rembang Hospital. It was hypothesized that most patients would receive first-line OAT regimens and experience side effects predominantly of moderate severity. Research Method: This study used a descriptive observational method with a cross-sectional design. Data were obtained retrospectively from the medical records of 106 patients with pulmonary tuberculosis receiving first-line OAT therapy at Bhina Bhakti Husada Rembang Hospital. The variables included patient characteristics, treatment patterns, types of OAT side effects, and severity of adverse drug reactions. Data were analyzed using univariate descriptive analysis. Results and Discussion: Most patients were aged 41-60 years (43.4%), male (64.2%), had a body weight of 30-49 kg (61.3%), and underwent treatment for 1-3 months (42.5%). The most common regimen was category 1 RHZE 2 FDC (39.6%). The most frequent side effects were reddish urine (100.0%), nausea and vomiting (83.0%), and flu syndrome (70.8%). Most side effects were categorized as moderate (56.6%). Implications: The findings emphasize the importance of routine monitoring and early management of OAT side effects, particularly during the early treatment phase. Further studies are needed to examine risk factors associated with severe adverse reactions and their impact on treatment adherence.

The Relationship between Stress Level and the Incidence of Gastritis in Final Year Pharmacy Students at the University of Muhammadiyah Kudus Nurul Shintya Dhevi; Endang Setyowati; Ulviani Yulia Husna
Advances in Healthcare Research Vol. 4 No. 1 (2026): September - February
Publisher : Yayasan Pendidikan Bukhari Dwi Muslim

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.60079/ahr.v4i1.715

Purpose: This study aimed to analyze the relationship between stress level and the incidence of gastritis among final-year Pharmacy students at the University of Muhammadiyah Kudus. It was hypothesized that higher stress levels would be associated with a greater incidence of gastritis. Research Method: This study employed a quantitative observational, cross-sectional design. The sample consisted of 103 seventh-semester Pharmacy students selected through purposive sampling. Stress level was measured using the Perceived Stress Scale-10 (PSS-10), while gastritis incidence was identified using a validated gastritis symptom questionnaire. Data were analyzed using univariate analysis and the Mann-Whitney test. Results and Discussion: Most respondents were 21 years old (63.1%), female (86.4%), and had no prior disease history (38.8%), although a history of stomach acid was common (32.0%). The majority experienced moderate stress (72.8%), and 20.4% experienced gastritis. Statistical analysis showed a significant relationship between stress level and gastritis incidence (p = 0.001), indicating that increasing stress level was associated with a higher risk of gastritis. Implications: These findings emphasize the importance of stress management and the promotion of digestive health among university students. Further research should include additional risk factors such as diet, sleep quality, and medication use.

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