Kumboyono Kumboyono
Brawijaya University

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Therapeutic adherence and somatic symptom perception in patients with heart failure: a scoping review Tri Andayani; Kumboyono Kumboyono; Lilik Supriati
International Journal of Public Health Science (IJPHS) Vol 15, No 2: June 2026
Publisher : Intelektual Pustaka Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/ijphs.v15i2.27004

Abstract

Heart failure is a chronic condition associated with high morbidity and frequent hospital readmissions, requiring effective self-management strategies. Therapeutic adherence and somatic symptom perception are essential components of self-management, enabling early symptom recognition and timely intervention. However, evidence regarding the relationship between these two factors remains limited. This scoping review aimed to map current evidence on the relationship between therapeutic adherence and somatic symptom perception in patients with heart failure and to identify influencing factors. The review followed the Joanna Briggs Institute methodology and PRISMA-ScR guidelines. Literature searches were conducted in ProQuest, ScienceDirect, Springer, and Google Scholar for studies published between 2016 and 2025. Eligible studies involved adult patients with heart failure and assessed therapeutic adherence and somatic symptom perception using validated instruments. Eight studies were included, comprising four cross-sectional studies, three randomized controlled trials, and one quasi-experimental study. Findings indicated a positive association between adherence to self-care behaviors and improved somatic symptom perception. Patients with consistent symptom monitoring demonstrated better recognition of early deterioration signs. However, a greater symptom burden was associated with lower adherence in several studies. Integrating symptom perception training, motivational strategies, and caregiver involvement may improve adherence, enhance early symptom detection, and reduce hospital readmissions.
The Effect of Polysaccharide Peptide (PsP) Administration on Lowering Triglyceride Level in Smokers with Dyslipidemia Titin Andri Wihastuti; Wiesye Roryn Sanyoto; Zahra Nazkiano; Faza Zahruna Fakhra; Kumboyono Kumboyono; Indah Nur Chomsy
Care : Jurnal Ilmiah Ilmu Kesehatan Vol 14, No 1 (2026): EDITION MARCH 2026
Publisher : Universitas Tribhuwana Tunggadewi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33366/jc.v14i1.7914

Abstract

Cigarette smoking is a major contributor to health problems worldwide and is highly prevalent in Indonesia, especially among young adult males. Nicotine in cigarettes disrupts lipid metabolism, leading to increased triglyceride levels and dyslipidemia, which are closely related to the double nutrition problem, characterized by abnormalities in the lipid profile. Smoking induces these abnormalities, indicating the need for antioxidant administration. This study aims to investigate the effect of Polysaccharide Peptides from Ganoderma lucidum on lowering triglycerides lipid profile level in active smokers with dyslipidemia. This experimental study used a pretest-posttest control group design involving 28 active smokers aged 18-21 years with dyslipidemia. Subjects were assigned to either a polysaccharide peptide (PsP) therapy group, receiving PsP extracted from Ganoderma lucidum, or a control group. Fasting serum triglyceride concentrations were measured before and after treatment. Statistical analyses used paired and unpaired t-tests to assess triglyceride level changes. The results showed a significant lowering of triglyceride levels in the PsP-treated group (p= 0.006). While the difference before and after PsP administration reached marginal statistical significance (p= 0.059), clinical improvement in triglyceride profiles was observed compared to controls. In conclusion, Ganoderma lucidum-derived PsP lowers triglyceride lipid profiles in smokers with dyslipidemia. These findings support the use of PsP as a therapeutic herbal intervention to improve lipid metabolism disturbed by smoking-induced inflammation.