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Effectiveness of Health Education and Short Message Service Reminders Reminders on Iron Supplement Adherence among Pregnant Women Nare Karapetyan; Lilit Toyonan; Michelle Steenvoorden; Nour Albahri
Journal of Health Innovation and Environmental Education Vol. 3 No. 1 (2026): June (On Going)
Publisher : Cahaya Ilmu Cendekia Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37251/jhiee.v3i1.2672

Purpose of the study: This study aimed to evaluate effectiveness structured health professional led education embedded within routine antenatal care in enhancing iron supplement adherence among pregnant women. Methodology: A quasi-experimental pretest–posttest control group design conducted among 120 pregnant women at Masis Maternity Hospital. Participants allocated to intervention group. receiving structured professional-led education with reinforcement or a control group receiving routine care. Primary outcome was iron supplement adherence (≥80% consumption), while secondary outcomes included knowledge score and hemoglobin level changes over 8 weeks. Data analyzed using chi-square tests, independent and paired t-tests, and logistic regression. Main Findings: After 8 weeks, adherence significantly increased to 81.0% in .intervention group compared with 51.7% in control group (p < 0.001). The intervention group was nearly five times more likely to achieve adequate adherence (AOR = 4.83; 95% CI: 2.01–11.61). Knowledge scores improved by +5.27 points in the intervention group versus +1.78 in controls (p < 0.001). Hemoglobin levels increased by 0.86 g/dL in intervention group icompared to 0.32 g/dL control group (p < 0.001). Novelty/Originality of this study: This study advances maternal health practice by reframing health education as a structured, professionally embedded care model rather than a single counseling encounter, demonstrating measurable behavioral and clinical impact within routine antenatal services.

Evaluation of Curcumin as NF-κB Inhibitor for Breast Cancer Therapy Using in Silico Approach Endang Adillah; Nour Albahri; Shrouk Ekramy
Journal of Academic Biology and Biology Education Vol. 2 No. 1 (2025): June
Publisher : Cahaya Ilmu Cendekia Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37251/jouabe.v2i1.1947

Purpose of the study: This study aims to evaluate the potential of curcumin as a breast cancer therapeutic agent by analyzing its ability to inhibit NF-κB activation using an in silico approach, specifically through molecular docking to assess absorption and interaction with the target protein. Methodology: This study used a quantitative experimental method with molecular docking as an in silico approach. Tools included a Lenovo laptop (Intel® Inside™, Windows 10 Pro). Software used: PyRx 0.8 (with AutoDock Vina), YASARA, PyMOL, and Discovery Studio 2019. Ligand data were obtained from PubChem; protein from Protein Data Bank. Lipinski’s Rule was applied for drug-likeness screening. Main Findings: Curcumin showed a binding affinity of -6.2 kcal/mol to NF-κB with RMSD < 2.00 Å. Visualization confirmed hydrogen bonds at ASN 32 and ASN 47, and hydrophobic pi-alkyl interactions at ALA 34 and ARG 50. Lipinski’s Rule of Five was fulfilled, indicating good oral drug-likeness and potential as an NF-κB inhibitor in breast cancer therapy. Novelty/Originality of this study: This study offers new insights into the potential of curcumin as a natural NF-κB inhibitor for breast cancer therapy through a comprehensive in silico approach. By combining molecular docking, visualization, and drug-likeness analysis, it advances current knowledge by highlighting curcumin’s binding efficiency and pharmacological feasibility, supporting its development as an alternative anticancer candidate.

Effectiveness of Health Education and Short Message Service Reminders Reminders on Iron Supplement Adherence among Pregnant Women Nare Karapetyan; Lilit Toyonan; Michelle Steenvoorden; Nour Albahri
Journal of Health Innovation and Environmental Education Vol. 3 No. 1 (2026): June (On Going)
Publisher : Cahaya Ilmu Cendekia Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37251/jhiee.v3i1.2672

Purpose of the study: This study aimed to evaluate effectiveness structured health professional led education embedded within routine antenatal care in enhancing iron supplement adherence among pregnant women. Methodology: A quasi-experimental pretest–posttest control group design conducted among 120 pregnant women at Masis Maternity Hospital. Participants allocated to intervention group. receiving structured professional-led education with reinforcement or a control group receiving routine care. Primary outcome was iron supplement adherence (≥80% consumption), while secondary outcomes included knowledge score and hemoglobin level changes over 8 weeks. Data analyzed using chi-square tests, independent and paired t-tests, and logistic regression. Main Findings: After 8 weeks, adherence significantly increased to 81.0% in .intervention group compared with 51.7% in control group (p < 0.001). The intervention group was nearly five times more likely to achieve adequate adherence (AOR = 4.83; 95% CI: 2.01–11.61). Knowledge scores improved by +5.27 points in the intervention group versus +1.78 in controls (p < 0.001). Hemoglobin levels increased by 0.86 g/dL in intervention group icompared to 0.32 g/dL control group (p < 0.001). Novelty/Originality of this study: This study advances maternal health practice by reframing health education as a structured, professionally embedded care model rather than a single counseling encounter, demonstrating measurable behavioral and clinical impact within routine antenatal services.

Evaluation of Curcumin as NF-κB Inhibitor for Breast Cancer Therapy Using in Silico Approach Endang Adillah; Nour Albahri; Shrouk Ekramy
Journal of Academic Biology and Biology Education Vol. 2 No. 1 (2025): June
Publisher : Cahaya Ilmu Cendekia Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37251/jouabe.v2i1.1947

Purpose of the study: This study aims to evaluate the potential of curcumin as a breast cancer therapeutic agent by analyzing its ability to inhibit NF-κB activation using an in silico approach, specifically through molecular docking to assess absorption and interaction with the target protein. Methodology: This study used a quantitative experimental method with molecular docking as an in silico approach. Tools included a Lenovo laptop (Intel® Inside™, Windows 10 Pro). Software used: PyRx 0.8 (with AutoDock Vina), YASARA, PyMOL, and Discovery Studio 2019. Ligand data were obtained from PubChem; protein from Protein Data Bank. Lipinski’s Rule was applied for drug-likeness screening. Main Findings: Curcumin showed a binding affinity of -6.2 kcal/mol to NF-κB with RMSD < 2.00 Å. Visualization confirmed hydrogen bonds at ASN 32 and ASN 47, and hydrophobic pi-alkyl interactions at ALA 34 and ARG 50. Lipinski’s Rule of Five was fulfilled, indicating good oral drug-likeness and potential as an NF-κB inhibitor in breast cancer therapy. Novelty/Originality of this study: This study offers new insights into the potential of curcumin as a natural NF-κB inhibitor for breast cancer therapy through a comprehensive in silico approach. By combining molecular docking, visualization, and drug-likeness analysis, it advances current knowledge by highlighting curcumin’s binding efficiency and pharmacological feasibility, supporting its development as an alternative anticancer candidate.

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