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Search 10.58578/ajstm.v2i2.5640 , by doi

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Peptic Ulcer Disease: A Comprehensive Review of Etiology, Diagnosis, and Modern Therapeutic Approaches Muhammad Akram; Isaac John Umaru; Abid Mahmood; Mohammed Khudhair Hasan; Hind A. Abdulghafoor; Fahad Said Khan; Fethi Ahmet Ozdemir; Gaweł Sołowski; Jaouher Ben Ali; Jehan Mohammed Al-Musawi
African Journal of Sciences and Traditional Medicine Vol 2 No 2 (2025): African Journal of Sciences and Traditional Medicine
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajstm.v2i2.5640

Abstract

Peptic ulcer disease (PUD) is an ailment of the gastrointestinal tract that is quite common and is marked by the development of open lesions known as ulcers in the stomach as well as in the proximal duodenum. It arises as a consequence of the imbalance between the protective enzymatic mechanisms of the mucosa, and the injurious agents like gastric acid, pepsin, Helicobacter pylori, and even non-steroidal anti-inflammatory drugs (NSAIDs). While many ulcers heal spontaneously, complications such as bleeding, perforation, and gastric outlet obstruction can lead to serious morbidity or mortality. With PUD, they can be treated and/or prevented if basic instruction is provided alongside a proper overview of the condition's etiological basis. In this case, pharmacological therapy and endoscopic procedures are heavily applicable.

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