Biomedical Journal of Indonesia
Vol 5, No 1 (2019)

RELATIONSHIP BETWEEN LUNG FUNCTION AND INTERLEUKIN-6 (IL-6) LEVELS IN THE POPULATION IN THE VICINITY OF THE GANDUS RUBBER FACTORY AND THE SUKAWINATAN WASTE DISPOSAL SITE IN PALEMBANG

Adela, Novita (Unknown)
Zulkarnain, Mohammad (Unknown)
Flora, Rostika (Unknown)



Article Info

Publish Date
31 Jan 2019

Abstract

Exposure to air pollution can interfere with the capacity of lung function and the body's immune system. Lung function capacity is the sum of two or more lung volumes. Interleukin-6 (IL-6) is an inflammatory mediator in respiratory pathogenesis. This study aims to determine the relationship between lung function and Interleukin-6 (IL-6) levels in the population around the Gandus Rubber Factory and Sukawinatan Landfill Palembang. The research design used is the type of correlation or explanatory that is examining the relationship between variables. A total of 72 samples were divided into 2 groups: groups in the Gandus Rubber Factory area and groups in the Sukawinatan Waste Disposal Site (Palembang). Lung function tests were measured using spirometry and Interleukin-6 levels were measured using ELISA examination. Chi square test results showed that there was no significant relationship (p value = 0.001) between lung function in the population around the Gandus Rubber Factory and Sukawinatan Waste Landfill. And there is no significant relationship (p value = 0.337) between Interleukin-6 (IL-6) levels in the population around the Gandus Rubber Factory and Sukawinatan Waste Landfill. Chi Square test results showed that there was no significant relationship (p value = 0.626) between lung function and Interleukin-6 (IL-6) levels in the population around the Gandus Rubber Factory. Chi Square test results showed that there was no significant relationship (p value = 1,000) between lung function and Interleukin-6 (IL-6) levels in the population around the Palembang Sukawinatan Landfill. Conclusions from the results of the study that there is no significant relationship (p <0.05) between levels of Interleukin-6 and Lung Function in the population around the Gandus Rubber Factory and Sukawinatan Landfill Palembang.

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Journal Info

Abbrev

bji

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology

Description

Biomedical Journal of Indonesia is an open access, peer-reviewed journal that focus on basic medical sciences, emphasizing on providing the molecular studies of biomedical problems and molecular mechanisms to integrate researches in all aspects of human health. BJI is dedicated to publishing ...