Nusantara Medical Science Journal
Volume 4 No. 2 Juli - Desember 2019

Profile And Treatment of Stevens-Johnson Syndrome Patients in DR. Soetomo General Hospital

Anggun Tera Rahmasari (Airlangga University)
Diah Mira Indramaya (Department of Dermatovenerolog, DR. Soetomo General Hospital)
Pudji Lestari (Department of Public Health, Airlangga University)



Article Info

Publish Date
18 Oct 2019

Abstract

Background: Stevens-Johnson Syndrome (SJS) is a rare but potentially life- threatening form of Severe Cutaneous Adverse Reaction (SCAR). SJS is mostly caused by drugs and is associated with high morbidity and mortality. Moreover, no standard treatment has been established for SJS. The aim of this study is to present epidemiological features, etiologies, clinical outcomes, medical histories, and treatments of SJS patients at the Inpatient Units Kemuning I and II Dr. Soetomo General Hospital between 2011 until 2015.Methods: This retrospective study used secondary data collected from medical records. All patients in the Inpatient Units Kemuning I and II of Dr. Soetomo General Hospital from the year 2011 until 2015 who was diagnosed SJS were included in this study.Result: There were 29 medical records consisting of 23 females and 6 males with the diagnosis of SJS found in 2011-2015. Most patients were aged 25-44 years old, with no family history of SJS. A majority first presented with a clinical history of fever. The main cause of SJS in this cohort was amoxicillin. Mucosal areas that were involved the most was the eye and mouth. Systemic treatments for patients were corticosteroid. The average duration of treatment was 15,88 days. None of the patients died.Conclusion: SJS was more common in females compared to males. The main systemic therapy in Inpatient Units Kemuning I dan II of Dr. Soetomo General Hospital was intravenous cortiosteroid and no patients died.

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Journal Info

Abbrev

jmednus

Publisher

Subject

Materials Science & Nanotechnology Neuroscience

Description

Nusantara Medical Science Journal (NMSJ) is an open access, peer-reviewed journal published by Faculty of Medicine, Hasanuddin University twice a year in June and December. NMSJ encompasses all basic and molecular aspects of medical sciences, with an emphasis on the molecular studies of biomedical ...