Garuda - Garba Rujukan Digital

Retrospective Study: Characteristic of Herpes Zoster Patients Ayuningati, Lia Kinasih; Indramaya, Diah Mira
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol 27, No 3 (2015): BIKKK DESEMBER 2015
Publisher : Faculty Of Medicine Airlangga University

Background: Herpes zoster (HZ) is a disease caused by the Varicella-zoster virus (VZV) that localized, primarily affects adults with characteristics of radicular pain, unilateral, and group of vesicles distributed according to dermatomes, innervated by a sensory nerve ganglion. Several risk factors for HZ is older populationand cellular immune dysfunction. Purpose: To evaluate general overview of HZ patients, hence better management can be provided. Methods: Retrospective study of newly diagnosed HZ patientsin Kemuning ward Dr. Soetomo General Hospital Surabaya during 2010-2013. Results: This study showed most commonly affected women (55.9%), themost common age was45-64 years old (40.7%)and the most common location was HZ thoracalis (31.4%). Conclusion: HZ is a common disease, which most commonly occured illness in elderlywith predisposing factors, that can determine the course of the disease, so we need proper management and education.Key words: herpes zoster, retrospective.

Retrospective Study: Atopic Dermatitis in Childhood Sihaloho, Kristina; Indramaya, Diah Mira
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol 27, No 3 (2015): BIKKK DESEMBER 2015
Publisher : Faculty Of Medicine Airlangga University

Background: Atopic dermatitis is a chronically and relapsing inflammatory skin disease affecting individuals with atopic history or their families. Atopic dermatitis affects all ageswith percentage 15-30% in children and 1-2% in adults. Chronic pruritus, skin infection, sleep disorder, and growth disorder are signs and symptomps commonly found in childhood atopic dermatitis. Evaluation of the profile and management of DA were needed to improve the management of atopic dermatitis. Purpose:To evaluate the profile of childhood atopic dermatitis. Methods: A retrospective study of all new cases of childhood atopic dermatitis who visited the Pediatric Division, Dermatology and Venereology Outpatient Clinic, Dr. Soetomo General Hospital, Surabaya from January 2007 to Desember 2011. Results: Numbers of chilhood atopic dermatitis increased from 2007 to 2011. Itchy was the main complaint of DA, but redness patches (32,3%) and xerosis cutis (9,1%) were also found. Atopic history in patients and or their families were found in 842 patients (74,3%). Treatment was antihistamin in 879 patients (77,5%). Conclusions: Chilhood atopic dermatitis are still increasing by years. Determining and avoiding trigger factors are education for DAs patients and their families in preventing it recurrency.Key words: atopic dermatitis, childhood, retrospective study.

Studi Retrospektif: Faktor Pencetus Akne Vulgaris Ayudianti, Prida; Indramaya, Diah Mira
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol 26, No 1 (2014): BIKKK APRIL 2014
Publisher : Faculty Of Medicine Airlangga University

Latar belakang: Akne vulgaris (AV) merupakan penyakit yang banyak diderita remaja, sekitar 85% remaja terkena dengan tingkat keparahan tertentu. Penyebab AV adalah multifaktorial. Faktor pencetus yang berperan antara lain faktor genetik, lingkungan, hormonal, stres emosi, makanan, trauma, kosmetik, dan obat-obatan. Tujuan: Mengidentifikasi faktor pencetus AV pada pasien di Divisi Kosmetik Medik Unit Rawat Jalan Kesehatan Kulit dan Kelamin RSUD Dr. Soetomo Surabaya. Metode: Studi retrospektif terhadap rekam medis tentang gambaran umum, faktor pencetus, diagnosis, dan penatalaksanaan pasien baru AV periode 2008-2010. Hasil: Jumlah pasien baru AV tahun 2008-2010 adalah 3448 pasien. Penderita AV perempuan (79,4%) lebih banyak daripada laki-laki. Kelompok umur terbanyak menderita AV adalah 15-24 tahun (64,3%), jenis pekerjaan pasien AV terbanyak adalah pelajar/mahasiswa (39,1%). Sebagian besar pasien menderita AV selama 1-5 tahun (46,5%). Faktor pencetus AV tersering adalah hormonal (55,6%). Tipe lesi AV terbanyak adalah papulopustular (75,6%). Terapi yang terbanyak adalah kombinasi doksisiklin oral, tretinoin dan klindamisin topikal. Simpulan: Faktor pencetus timbulnya AV pada wanita tersering adalah hormonal dan kosmetik, sedangkan pada laki-laki adalah makanan dan stres. Kata kunci: akne vulgaris, faktor pencetus, retrospektif.

Kadar Kortisol Serum Pasien Eritema Nodosum Leprosum (ENL) Baru Ayudianti, Prida; Suyoso, Sunarso; Indramaya, Diah Mira
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol 26, No 2 (2014): BIKKK AGUSTUS 2014
Publisher : Faculty Of Medicine Airlangga University

Latar belakang: Eritema nodosum leprosum (ENL) yang merupakan komplikasi serius dari kusta tipe multibasiler, merupakan bentuk reaksi hipersensitivitas tipe III menurut Gell dan Combs. Karakteristik reaksi ENL adalah peningkatan sitokin proinflamasi TNF-a dan IL-1. Pelepasan sitokin proinflamasi kronis dapat menyebabkan gangguan produksi kortisol. Tujuan: Mengevaluasi kadar kortisol serum pasien kusta dengan ENL baru, berdasarkan lamanya pemberian Multidrugs Therapy (MDT) dan derajat keparahan ENL. Metode: Dilakukan pemeriksaan kadar kortisol serum terhadap 14 pasien ENL baru, yang berusia 15 tahun, belum pernah mendapat terapi kortikosteroid atau telah mendapatkan terapi kortikosteroid maksimal 3 minggu. Hasil: Didapatkan 14 sampel dengan rerata kadar kortisol serum pada pasien BL 9,06 (SE 2,84) g/dL, tipe LL 8,83 (SE 3,37) g/dL, pasien ENL baru yang mendapat MDT < 6 bulan 2,11 (SE 0,51) g/dL, mendapat MDT 6 bulan 14,40 (SE 2,65) g/dL, pasien ENL dengan derajat keparahan ringan 19,05 (SE 0) g/dL, sedang 7,75 (SE 2,75) g/dL, berat 8,56 (SE 3,29) g/dL. Nilai normal kadar kortisol serum adalah 10 g/dl ( 276 nmol/l). Simpulan: Pasien kusta tipe MB dengan ENL baru didapatkan rerata kadar kortisol serum dibawah normal. Hasil yang sama juga didapatkan pada pasien dengan riwayat pemberian MDT < 6 bulan yang memiliki derajat keparahan ENL sedang dan berat.Kata kunci : eritema nodosum leprosum, kortisol serum, MDT, derajat keparahan.

Salivary Cortisol Levels Representing Serum Cortisol Levels in Atopic Dermatitis Patients Adisty, Novia Indriyani; Hutomo, Marsudi; Indramaya, Diah Mira
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol 27, No 3 (2015): BIKKK DESEMBER 2015
Publisher : Faculty Of Medicine Airlangga University

Background: Atopic dermatitis (AD) is a chronic inflammatory skin disorder, recurrent lesion with a distinctive and specific distribution of lesions according phases. Patients with allergic diseases have been known to have a variety of patterns of cortisol. Dysfunction of the hypothalamic-pituitary-adrenal (HPA) axis and the role of cortisol has been studied in patients with DA. Free cortisol adrenal cortex is considered biologically active, which passively diffuses into all body fluids including saliva. Another advantage is the saliva examination is non-invasive, stress free and easy to do anywhere. Purpose: To analyze the correlation between levels of serum cortisol and salivary cortisol in patients with AD. Methods: Analytical, observational, cross-sectional study of the 29 AD patients who underwent blood and saliva samples by the method of "passive drooling" conducted on the hour 8:00 to 9:00 to see the levels of serum cortisol and salivary cortisol. Results: Twenty-nine subjects revealed mean serum cortisol levels 6,703,82g/dL, mean salivary cortisol levels was 1,430,96g/dL. Equation of salivary cortisol = 0,471+0,142*serum cortisol 2 (R=28,5%). Conclusions: The increasing of serum cortisol level of AD patients will result in increased levels of cortisol in saliva. Saliva collection methods by âpassive droolingâ were able to describe the serum cortisol levels at 28,5%.Key words: atopic dermatitis, serum cortisol, salivary cortisol.

Relationship between Diet, Cosmetics and Degree of Acne Vulgaris in Dermatovenereology Outpatients at Dr. Soetomo General Hospital, Surabaya Mah Zhook Yueng; Diah Mira Indramaya; Arifa Mustika
Althea Medical Journal Vol 5, No 4 (2018)
Publisher : Faculty of Medicine Universitas Padjadjaran

Background: Acne vulgaris (AV) is a chronic inflammatory multifactorial disease that involves the pilosebaceous unit. The lesions of acne may be either non-inflammatory (comedones, which are blackheads or whiteheads) or inflammatory lesions (papules, nodules or pustules). The effects of diet and cosmetics on acne are still inconclusive. The objective of this study was to analyse the relationship between diet, cosmetics and the degree of AV.Methods: This was a hospital-based, analytic observational study with cross-sectional design. The subjects were patients from the Outpatient Clinic of Dermatovenereology Department of Dr. Soetomo General Hospital. The questionnaire was filled by the respondents and the degree of AV was graded by the specialist. Results: Among the types of diet, white bread (p=0.039), chocolate (p=0.044) and oily food (p=0.013) are significantly associated with the degree of AV. However, white rice, potatoes and milk were insignificantly related to degree of AV (p>0.05). No significant association was found in cosmetics (cleanser, moisturizer, facial protection, exfoliators and decorative cosmetics) with the degree of AV (p>0.05).Conclusions: The factors that have an influence on the degree of AV are white bread, chocolate and oily food intake.

Profile And Treatment of Stevens-Johnson Syndrome Patients in DR. Soetomo General Hospital Anggun Tera Rahmasari; Diah Mira Indramaya; Pudji Lestari
Nusantara Medical Science Journal Volume 4 No. 2 Juli - Desember 2019
Publisher : Faculty of Medicine, Hasanuddin University.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/nmsj.v4i2.5696

Background: Stevens-Johnson Syndrome (SJS) is a rare but potentially life- threatening form of Severe Cutaneous Adverse Reaction (SCAR). SJS is mostly caused by drugs and is associated with high morbidity and mortality. Moreover, no standard treatment has been established for SJS. The aim of this study is to present epidemiological features, etiologies, clinical outcomes, medical histories, and treatments of SJS patients at the Inpatient Units Kemuning I and II Dr. Soetomo General Hospital between 2011 until 2015.Methods: This retrospective study used secondary data collected from medical records. All patients in the Inpatient Units Kemuning I and II of Dr. Soetomo General Hospital from the year 2011 until 2015 who was diagnosed SJS were included in this study.Result: There were 29 medical records consisting of 23 females and 6 males with the diagnosis of SJS found in 2011-2015. Most patients were aged 25-44 years old, with no family history of SJS. A majority first presented with a clinical history of fever. The main cause of SJS in this cohort was amoxicillin. Mucosal areas that were involved the most was the eye and mouth. Systemic treatments for patients were corticosteroid. The average duration of treatment was 15,88 days. None of the patients died.Conclusion: SJS was more common in females compared to males. The main systemic therapy in Inpatient Units Kemuning I dan II of Dr. Soetomo General Hospital was intravenous cortiosteroid and no patients died.

RETROSPECTIVE STUDY: INITIAL PHARMACOTHERAPY PROFILE OF NEW ACNE VULGARIS PATIENTS Esravila Ariya Wibisono; Diah Mira Indramaya; Maftuchah Rochmanti
Jurnal Berkala Epidemiologi Vol. 8 No. 3 (2020): Jurnal Berkala Epidemiologi (Periodic Epidemiology Journal)
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jbe.V8I32020.236-245

Background: Acne Vulgaris (AV) is one of the most common diseases in the field of dermatology and ranks as the eighth most prevalent disease worldwide. Early management of this potentially deforming skin disease may reduce the pathophysiological burden and improve the quality of life of patients. Purpose: This study aimed to determine the pharmacotherapy for new patients with AV. Methods: This cross-sectional study used new patients with AV of the Cosmetic Division of the Outpatient Skin and Venereal Health Unit, Regional Public Hospital (RSUD) Dr. Soetomo, from January to December 2013 that were descriptively presented. The variable was the pharmacotherapy given. This study used secondary data collection by looking at the patients’ medical records. The variables studied were acne lesions and pharmacotherapy regimens, including the administration route and the medicine used. Results: The number of samples that met the inclusion criteria was 951 patients. Comedonal acne was most commonly given topical tretinoin. Papulopustular acne was most commonly given a topical combination of clindamycin and tretinoin, while acne conglobata was most commonly given a combination of topical clindamycin and tretinoin with oral doxycycline. Conclusion: The new patients with comedonal acne were mostly prescribed topical tretinoin pharmacotherapy. A pharmacotherapy combination of topical clindamycin and tretinoin was given to most new patients with papulopustular acne, whereas new patients with conglobata acne were given a pharmacotherapy combination of topical tretinoin and clindamycin with oral doxycycline.

Studi Retrospektif: Faktor Pencetus Akne Vulgaris Prida Ayudianti; Diah Mira Indramaya
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 26 No. 1 (2014): BIKKK APRIL 2014
Publisher : Faculty of Medicine, Universitas Airlangga

Latar belakang: Akne vulgaris (AV) merupakan penyakit yang banyak diderita remaja, sekitar 85% remaja terkena dengan tingkat keparahan tertentu. Penyebab AV adalah multifaktorial. Faktor pencetus yang berperan antara lain faktor genetik, lingkungan, hormonal, stres emosi, makanan, trauma, kosmetik, dan obat-obatan. Tujuan: Mengidentifikasi faktor pencetus AV pada pasien di Divisi Kosmetik Medik Unit Rawat Jalan Kesehatan Kulit dan Kelamin RSUD Dr. Soetomo Surabaya. Metode: Studi retrospektif terhadap rekam medis tentang gambaran umum, faktor pencetus, diagnosis, dan penatalaksanaan pasien baru AV periode 2008-2010. Hasil: Jumlah pasien baru AV tahun 2008-2010 adalah 3448 pasien. Penderita AV perempuan (79,4%) lebih banyak daripada laki-laki. Kelompok umur terbanyak menderita AV adalah 15-24 tahun (64,3%), jenis pekerjaan pasien AV terbanyak adalah pelajar/mahasiswa (39,1%). Sebagian besar pasien menderita AV selama 1-5 tahun (46,5%). Faktor pencetus AV tersering adalah hormonal (55,6%). Tipe lesi AV terbanyak adalah papulopustular (75,6%). Terapi yang terbanyak adalah kombinasi doksisiklin oral, tretinoin dan klindamisin topikal. Simpulan: Faktor pencetus timbulnya AV pada wanita tersering adalah hormonal dan kosmetik, sedangkan pada laki-laki adalah makanan dan stres. Kata kunci: akne vulgaris, faktor pencetus, retrospektif.

Kadar Kortisol Serum Pasien Eritema Nodosum Leprosum (ENL) Baru Prida Ayudianti; Sunarso Suyoso; Diah Mira Indramaya
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 26 No. 2 (2014): BIKKK AGUSTUS 2014
Publisher : Faculty of Medicine, Universitas Airlangga

Latar belakang: Eritema nodosum leprosum (ENL) yang merupakan komplikasi serius dari kusta tipe multibasiler, merupakan bentuk reaksi hipersensitivitas tipe III menurut Gell dan Combs. Karakteristik reaksi ENL adalah peningkatan sitokin proinflamasi TNF-a dan IL-1. Pelepasan sitokin proinflamasi kronis dapat menyebabkan gangguan produksi kortisol. Tujuan: Mengevaluasi kadar kortisol serum pasien kusta dengan ENL baru, berdasarkan lamanya pemberian Multidrugs Therapy (MDT) dan derajat keparahan ENL. Metode: Dilakukan pemeriksaan kadar kortisol serum terhadap 14 pasien ENL baru, yang berusia 15 tahun, belum pernah mendapat terapi kortikosteroid atau telah mendapatkan terapi kortikosteroid maksimal 3 minggu. Hasil: Didapatkan 14 sampel dengan rerata kadar kortisol serum pada pasien BL 9,06 (SE 2,84) g/dL, tipe LL 8,83 (SE 3,37) g/dL, pasien ENL baru yang mendapat MDT < 6 bulan 2,11 (SE 0,51) g/dL, mendapat MDT 6 bulan 14,40 (SE 2,65) g/dL, pasien ENL dengan derajat keparahan ringan 19,05 (SE 0) g/dL, sedang 7,75 (SE 2,75) g/dL, berat 8,56 (SE 3,29) g/dL. Nilai normal kadar kortisol serum adalah 10 g/dl ( 276 nmol/l). Simpulan: Pasien kusta tipe MB dengan ENL baru didapatkan rerata kadar kortisol serum dibawah normal. Hasil yang sama juga didapatkan pada pasien dengan riwayat pemberian MDT < 6 bulan yang memiliki derajat keparahan ENL sedang dan berat.Kata kunci : eritema nodosum leprosum, kortisol serum, MDT, derajat keparahan.

Title

Found 47 Documents
Search

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Title Search

Found 47 Documents Search

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Title

Found 47 Documents
Search