Jurnal Ilmu dan Kesehatan Hewan
Vol 2 No 1 (2014)

Sensitifitas dan Spesifisitas Teknik Imunohistokimia Rabies

I Ketut Wirata (Unknown)
I Ketut Berata (Unknown)
I Ketut Puja (Unknown)



Article Info

Publish Date
01 Feb 2014

Abstract

Fluorescent Antibody Test (FAT) is a golden standard for rabies diagnosis, but it requires many sample preconditions before testing. Immunohistochemical technique (IHC) has the same principle as the FAT, however, it is more simple. This study was conducted to examine the sensitivity and specificity of IHC compare to FAT. The sensitivity and specificity were calculated using the formula of 2 x 2 contingency table and statistical analysis of the chi-square. Out of 40 samples that rabies positive on FAT, 27 samples (67.5%) showed rabies positive on IHC and 13 samples (32.5%) showed rabies negative on IHC. All samples that rabies negative on FAT were also rabies negative on IHC. The IHC has the sensitivity and specificity level 67.5% and 100% respectively. The IHC has a lower sensitivity than FAT, however, IHC has many advantages such as it can be performed on formalin fixed-samples. A further research is necessary to improve the sensitivity of IHC on detecting the rabies.

Copyrights © 2014






Journal Info

Abbrev

jikh

Publisher

Subject

Health Professions Veterinary

Description

Jurnal Ilmu dan Kesehatan Hewan menerima naskah ilmiah original (belum pernah dipublikasikan) dalam bidang veteriner atau yang terkait dengannya. Jurnal Ilmu dan Kesehatan Hewan dikelola oleh Program Studi Magister Kedokteran Hewan Universitas Udayana dan terbit dua kali ...