Buletin Veteriner Udayana
Vol. 11 No. 2 Agustus 2019

Kesembuhan Fraktur Tulang Femur Kelinci Pasca Implantasi Bahan Cangkok Demineralisasi Serbuk Tulang Sapi Bali

Ni Putu Trisna Asih (Praktisi Dokter Hewan Gianyar di Blahbatuh, Batuan Kaler, Sukawati Gianyar, Bali, Indonesia 80582)
I Wayan Wirata (Laboratorium Bedah Veteriner, Fakultas Kedokteran Hewan Universitas Udayana, Jl. PB Sudirman, Denpasar, Bali, Indonesia 80225.)
Luh Made Sudimartini (Laboratorium Farmakologi dan Farmasi Veteriner, Fakultas Kedokteran Hewan Universitas UdayanaJl. PB Sudirman, Denpasar, Bali, Indonesia 80225.)
Ida Bagus Oka Winaya (Laboratorium Patologi Veteriner, Fakultas Kedokteran Hewan Universitas Udayana, Jl. PB. Sudirman Denpasar Bali, Indonesia 80225.)
I Made Kardena (Laboratorium Patologi Veteriner, Fakultas Kedokteran Hewan Universitas Udayana, Jl. PB. Sudirman Denpasar Bali, Indonesia 80225.)
I Wayan Gorda (Laboratorium Bedah Veteriner, Fakultas Kedokteran Hewan Universitas Udayana, Jl. PB Sudirman, Denpasar, Bali, Indonesia 80225.)



Article Info

Publish Date
31 Aug 2019

Abstract

The purpose of this study to determine the microscopic changes in rabbit femur fracture healing post-implantation of the graft material demineralized powder bone of bali cattle. Twelve local male rabbits were divided into two groups randomly. Group A consisted of three rabbits used as a control, in which the diaphysis rabbit femur bones were drilled with a diameter of 5mm and depth of drill to reach the medulla, without giving graft material. Group B nine rabbits that were drilled the same as group A and given a powder bone graft. Monitoring progress of bone healing was done in a row against one rabbits in group A and group B three rabbits at week 2nd, 4th, and 6th post-surgery with biopsy for sampling bone subsequently prepared to see microscopic changes the bone with using hematoxylin-eosin (HE) staining. The results showed that the group B bone healing observ by reducing inflammation, proliferation of fibrolast, osteoblasts, osteoclasts, osteocytes, woven bone, trabecular bone, and neovascularization. In conclusion, the origin of the bone graft material bali cattle was able to induce the healing process of bone fractures in rabbits.

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