Jurnal Natur Indonesia
Vol 17, No 2 (2019)

Synthesis, Characterization and Anti Mcf-7 Proliferative Acitivity of Flavonol Derivatives of 2'-Hydroxyacetophenon and 3,4,5-Dimethoxy Benzaldehid

Rokim, Muhamad (Unknown)
Zamri, Adel (Unknown)
Teruna, Hilwan Yuda (Unknown)

Article Info

Publish Date
30 Oct 2019

Abstract

Flavonols a derivatives of 2'-hydroxyacetophenon and 3,4,5-dimethoxy benzaldehid has been synthesized under basic condition (KOH). The structure of the compound was characterized based on the interpretation of spectroscopic data, including UV, FTIR, NMR and HRMS. Anticancer activity was evaluated using the MTS assay against MCF-7 cells, which showed that the flavonol 2'-hydroxycalone derivative was potentially active as an anticancer substance with IC50 values <1000 µg / mL.

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Journal Info
Jurnal Natur Indonesia
Website

Abbrev

JN

Publisher

Universitas Riau

Subject

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry

Description

Jurnal Natur Indonesia published since 1998, is a science journal that presents articles on research results, thoughts and views from researchers and experts in the field of biosciences (basic science), including biology, physics, chemistry and mathematics. In the field of biosciences (basic ...