Interleukin-10 of Positive and Negative HIV RNA Patients in Dr. Moewardi General Hospital in Surakarta

Emirita Wulan Pradeta (Sebelas Maret University)
Afiono Agung Prasetyo (Sebelas Maret University)
Yulia Sari (Sebelas Maret University)

Nexus Biomedika
Vol 4, No 2 (2015): Nexus Biomedika

Background: HIV infection may cause imbalance of immune system and impacts on IL-10 status which has several immunological roles that may affect HIV infection itself. The aim of this study was to investigate the association between IL-10 and HIV RNA status. Methods: The IL-10 levels in the plasma samples obtained from 60 HIV patients in Dr. Moewardi General Hospital in Surakarta were analyzed by ELISA (Enzyme-Linked Immunosorbent Assay). Results: Elevated IL-10 level was found in 21.7% (13/60) samples and predominantly in positive HIV RNA (OR 2.67; 95% CI 0.40-17.96) and male (OR 1.22; 95% CI 0.36-4.17) patients. Conclusion: Elevated IL-10 level was associated with positive HIV RNA status and gender. Keywords: IL-10, HIV RNA