Paediatrica Indonesiana
Vol 39 No 9-10 (1999): September - October 1999

lmmunomodulatory Effects of Human Milk upon Immune Functions in Infants

Ariyanto Harsono (Department of Child Health, Airlangga University Medical School/Dr. Soetomo Hospital, Surabaya, East Java)
Anang Endaryanto (Department of Child Health, Airlangga University Medical School/Dr. Soetomo Hospital, Surabaya, East Java)
Muhammad Faizi (Department of Child Health, Airlangga University Medical School/Dr. Soetomo Hospital, Surabaya, East Java)



Article Info

Publish Date
30 Oct 1999

Abstract

Human milk is capable to modulate the immune system in infants in several ways. lmmunorestoration is mostly dominated by immunoglobulins content of human milks especially secretory lgA, although lgG antibody also plays important role. Nucleotide content of human milk is among substances widely investigated all over the world, capable to potentiate immune response in infants by increasing NK cell activity and production of lL-2. lmmunopotentiation also the result of cell content activity of human milk, interferon, and complement. Special feature of anti-inflammatory property  of human milk is its capability to prevent of allergic disease in infants. This because ofprotein in breast milk is species specific, instead the role of secretotry lgA in  preventing absorption of foreign macromolecules. Other substances also play an important role in the antiinflammatory properties of human milk and interestingly the paucity of initiators and mediators in human milk.

Copyrights © 1999






Journal Info

Abbrev

paediatrica-indonesiana

Publisher

Subject

Health Professions Medicine & Pharmacology

Description

Paediatrica Indonesiana is a medical journal devoted to the health, in a broad sense, affecting fetuses, infants, children, and adolescents, belonged to the Indonesian Pediatric Society. Its publications are directed to pediatricians and other medical practitioners or researchers at all levels of ...