Isolation and Antioxidant and Antibacterial Activity of Flavonoid from Ficus variegate Blume

Rolan Rusli (Faculty of Pharmacy, University of Mulawarman, Samarinda, East Kalimantan)
Bela Apriliana Ningsih (Faculty of Pharmacy, University of Mulawarman, Samarinda, East Kalimantan)
Agung Rahmadani (Faculty of Pharmacy, University of Mulawarman, Samarinda, East Kalimantan)
Lizma Febrina (Faculty of Pharmacy, University of Mulawarman, Samarinda, East Kalimantan)
Vina Maulidya (Faculty of Pharmacy, University of Mulawarman, Samarinda, East Kalimantan)
Jaka Fadraersada (Faculty of Pharmacy, University of Mulawarman, Samarinda, East Kalimantan)

Indonesian Journal of Chemistry
Vol 19, No 2 (2019)

Ficus variegata Blume is specific plant of east Kalimantan. Flavonoid compound of Ficus variegata Blume was isolated by vacuum liquid and column chromatography, with previously extracted by maceration method using n-hexane and methanol, and fractination using ethyl acetate solvent. Eluent used in isolation were n-hexane:ethyl acetate (8:2). The results of elucidation structure by using spectroscopy methods (GC-MS, NMR, and FTIR) was obtained 5-Hidroxy-2-(4-methoxy-phenyl)-8,8-dymethyl-8H-pyrano[2,3-f] chromen-4-one. This compound has an antibacterial and antioxidant activities.