Indonesian Journal of Chemistry
Vol 20, No 1 (2020)

Antibacterial Activity of Silver Nanoparticles Capped by p-Aminobenzoic Acid on Escherichia coli and Staphylococcus aureus

Dian Susanthy (Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Gadjah Mada, Sekip Utara BLS 21, Bulaksumur, Yogyakarta 55281, Indonesia)
Sri Juari Santosa (Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Gadjah Mada, Sekip Utara BLS 21, Bulaksumur, Yogyakarta 55281, Indonesia)
Eko Sri Kunarti (Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Gadjah Mada, Sekip Utara BLS 21, Bulaksumur, Yogyakarta 55281, Indonesia)



Article Info

Publish Date
31 Dec 2019

Abstract

This paper describes the antibacterial performance of silver nanoparticles (AgNPs) which have been synthesized by using p-aminobenzoic acid as reducing and stabilizing agent simultaneously. The silver nitrate with various concentrations was reacted with pH 11-adjusted p-aminobenzoic acid with a concentration of 5 Ɨ 10–3 mol L–1 for 30 min in a boiling water bath. The synthesized AgNPs were characterized by UV-Vis spectrophotometry, Transmission Electron Microscope (TEM), and Particle Size Analyzer (PSA). The antibacterial performance of the synthesized AgNPs was evaluated by agar well diffusion method on Escherichia coli and Staphylococcus aureus. The higher silver nitrate concentration, the bigger the nanoparticle size, the wider particle size distribution, and the higher number of AgNPs formed. AgNPs synthesized from higher silver nitrate concentration had higher antibacterial activity. It is an indication that the antibacterial activity of AgNPs is mainly controlled by the silver ion concentration which influences the AgNPs particle size and existence of silver ion in the AgNPs colloidal solution

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Journal Info

Abbrev

ijc

Publisher

Subject

Chemical Engineering, Chemistry & Bioengineering Chemistry

Description

Indonesian Journal of Chemistry is an International, peer-reviewed, open access journal that publishes original research articles, review articles, as well as short communication in all areas of chemistry including applied chemistry. The journal is accredited by The Ministry of Research, Technology ...