The extract of leaf, fruit and tree bark of tembelekang (L. camara Linn.) as antibacterial activity to Staphylococcus aureus and Escherichia coli has been studied using agar diffusion method. The extract producted with extraction with maseration fraction teqnique. The aim of this research is to show the potential L. camara plant as antibacterial to against Staphylocuccus aureus and Escherichia coli. The research result showed that extract of leaf of L. camara plant having potency as antibacterial and showing that there is a real correlation between the L. camara plant as the medicinal plant and the bioactive compounds contained in it.
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