Pena Medika : Jurnal Kesehatan
Vol 6, No 2 (2016): PENA MEDIKA JURNAL KESEHATAN

Formulasi Self-Nanoemulsifying Drug Delivery System (SNEDDS) Ekstak Daun Pepaya (Carica papaya L.) dengan Virgin Coconut Oil (VCO) sebagai Minyak Pembawa

Metha Anung Anindhita (Unknown)
Nila Oktaviani (Unknown)

Article Info

Publish Date
09 Mar 2017

Abstract

Background. Treatment with natural substances have side effect that are quite small compare to chemicals. Papaya leaves contain flavonoids that have analgesic effect. Flavonoid inhibits the production of prostaglandins. This study was conducted toformulate a papaya leave extract into Self-Nanoemulsifying Drug Delivery System (SNEDDS) technique. Method. Papaya leaves extract SNEDDS made with Virgin Coconut Oil (VCO) as oil, tween 80 as surfactant, and PEG 400 as cosurfactant. The nanoemulsion tested clarity, transmittance, emulsification time and stability. Result. Papaya leaves extract SNEDDS can be produced with VCO as oil and surfactantcosurfactan in 1:9. Keyword: papaya leaves extract, snedds, virgin coconut oil 

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Journal Info
Pena Medika : Jurnal Kesehatan
Website

Abbrev

medika

Publisher

Universitas Pekalongan

Subject

Health Professions Medicine & Pharmacology Nursing Public Health Veterinary

Description

Focus And Scope Pena Medika is a national journal that contains the results of research on public health science and practice. Aimed at all practitioners and researchers in the field of public health to improve the degree of Public Health. PENA MEDIKA were first published in June 2010 and published ...