<![CDATA[Osteoarthritis (OA) is a degenerative bone disease that begin by loss of articulary cartilage (joint). The disease most commonly affects the elder or adult people. Elderly people experiencing degenerative processes in which decreasing organ function. The organ degeneration causes several diseases resulting the patients to receive multi drug for the treatment and causing polypharmacy, thus will increase the risk of drug interactions. This study was conducted to determine the treatment for osteoarthritis and drug interactions that occur in patients with osteoarthritis. The method used was total sampling using the descriptive-retrospective approach. The sample was elderly osteoarthritis patients in outpatient installation which were treated in RSD dr. H Koesnadi Bondowoso during January to December 2013. In this study we found that the main treatment for osteoarthritis was non steroidal anti inflammatory drug (NSAID) that use to relief pain. From 108 samples of elderly osteoarthritis patients, we found that 17 patients (15.74%) indicating the potential for drug interactions. Keywords: osteoarthritis, outpatient age above 60 years, NSAID, drug interaction]]>
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