Chemistry Indonesian Journal of Chemical Research
Vol 2 No 1 (2014): Edisi Bulan Juli (Edition For July)

Oleanan Derivate Compounds From Melochia umbellata (Houtt) Stapf var. Degrabrata K Bark And Their Bioactivity

Usman, Usman (Unknown)
Soekamto, Nunuk H. (Unknown)
Usman, Hanapi (Unknown)
Ahmad, Ahyar (Unknown)

Article Info

Publish Date
31 Jul 2014

Abstract

Oleanan derivated 3-acetyl-12-oleanen-28-oat has been isolated from the n-hexane fraction of M. umbellata(Houtt) Stapf var. degrabrata K. bark. The molecular structure were determined by IR spectroscopy, 1D and 2DNMR (1H, 13C, DEPT, COSY, HMQC and HMBC) data analysis. Bioactivity tested results indicated that thecompound was toxic to A. salina with LC50 value was 361.93 mg/mL. At the concentration of 1000 mg/mL 3acetyl-12-oleanen-28-oat gave the highest inhibition to bacteria B. subtilis and the fungus C. albicans with the inhibited zone diameter was 15.8 mm and 15.2 mm, res.

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Journal Info
Chemistry Indonesian Journal of Chemical Research
Website

Abbrev

Indonesian Journal of Chemical Research (Indones.

Publisher

Universitas Pattimura

Subject

Biochemistry, Genetics & Molecular Biology Chemistry Engineering Environmental Science

Description

Indo. J. Chem. Res. is a journal that regularly publishes primary articles covering all branches of chemistry and its sub-disciplines. Published articles consist of complete research, short communication, and review articles. The scope of published articles is not limited to inorganic chemistry, ...