Chemistry Indonesian Journal of Chemical Research
Vol 4 No 1 (2016): Edisi Bulan Juli (Edition For July)

Sintesis Senyawa N-fenetil 4-O-asetil ferulamida dari Asam Ferulat melalui Reaksi Amidasi Tidak Langsung

Islam, Muhammad Fajar (Unknown)
Firdaus, Firdaus (Unknown)
Soekamto, Nunuk H. (Unknown)

Article Info

Publish Date
31 Jan 2016

Abstract

Compound N-phenetyl 4-O-asetil ferulamide had been synthesized from ferulic acid and phenetylamine through esterification and indirect amidation method. Esterification reaction of ferulic acid with anhydride acetate was done in pyridine solvent at room temperature. Indirect amidation was perform by chlorination using tionyl chloride in benzene solvent at 70°C and continued by amidation with phenetylamine, catalyzed by pyridine in dichloromethane solvent at room temperature. the compound obtained is brown yellowish crystal with melting point 118-120°C. The rendemen of target compound is 53.81%.

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Journal Info
Chemistry Indonesian Journal of Chemical Research
Website

Abbrev

Indonesian Journal of Chemical Research (Indones.

Publisher

Universitas Pattimura

Subject

Biochemistry, Genetics & Molecular Biology Chemistry Engineering Environmental Science

Description

Indo. J. Chem. Res. is a journal that regularly publishes primary articles covering all branches of chemistry and its sub-disciplines. Published articles consist of complete research, short communication, and review articles. The scope of published articles is not limited to inorganic chemistry, ...