Jurnal farmasi UIN Alauddin Makassar
Vol 8 No 1 (2020): Jurnal Farmasi Edisi Mei

UJI AKTIVITAS FRAKSI EKSTRAK BIJI BELIGO (Benincasa hispida Thunb. Cogn) TERHADAP PENURUNAN KADAR GLUKOSA DARAH MENCIT

M. Rusdi (Jurusan Farmasi FKIK UIN Alauddin Makassar)



Article Info

Publish Date
27 May 2020

Abstract

This research aims to determine the faction activity of n-hexane, ethyl acetat, and 70% beligo seeds (Benincasa hispida Thunb. Cogn) on the decrease in blood glucose levels in mice. The research method includes extraction of samples by macerasion using 96% liquid of ethanol filter. This research used 25 male mice as he test animals which were divided into 5 treatment groups. Mice were fasted for 8 hours before treatment, then measurement of initial glucose levels, after that they were induced with 10% glucose and glucose levels were measured after induction. Group I was given 0,5% Na-CMC suspense as negative control, group II was given the n-hexane fraksion, group III was given ethyl acetate fraction, group IV was given 70% ethanol fraction and group V was given 0,013 mg/20 g BB glibenclamide suspension as positive control. Giving is done perorally with a volume of 1 ml. The results showed that the faction of n-hexane, ethyl acetate, and 70% ethanol extracts of beligo seeds (Benincasa hispida Thunb. Cogn) with a dose 28 mg/20 g BB had activity in decreasing blood glucose levels in mice (Mus musculus).

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Journal Info

Abbrev

jurnal_farmasi

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

Description

Jurnal Farmasi diterbitkan oleh Jurusan Farmasi UIN Alauddin Makassar. Jurnal ini terbit 2 kali dalam setahun dengan tema seputar ilmu kefarmasian, yang mencakup Sains Farmasi, Farmasi Klinik dan Komunitas, serta Manajemen ...