Patients with HIV_AIDS have an increased risk to develop neurological disorders include a complicationof intracerebral mass. Primary CNS tumors in this condition are rare and difficult to diagnose because it hasuncommon presentation, unusual tumor growth and manifests at a young age in a patient with HIV-AIDS.Advanced imaging techniques with contrast-enhanced magnetic resonance scans should be used to guidediagnosis in this condition. in a patient with HIV-AIDS, biopsy should be carried out if standard imagingshowed atypical features or in a patient who has a poor response to empirical treatment for neurotoxoplasmosis.In this case, we reported a case of A 26 years old male with HIV-AIDS with neurological deficits who laterdiagnosed with glioblastoma.
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