<![CDATA[Valproate is used for various neurological and psychiatric conditions. It has various adverse effects, mostof which are mild and transient, however, hyperammonaemia in the absence of abnormal liver functionis an uncommon and life-threatening side effect. The exact mechanism for this is unknown, but severalmechanisms have been described for the same. We present a case of 11-year-old male patient belongingto a broken family. Initially he was diagnosed as a case of ADHD with conduct disorder. However due tonon-response to medications, over time, a EEG was done and was found to have generalised epileptiformdischarges, He was maintaining well on Valproate, but had an acute exacerbation of symptoms on beingoff medications for 2 weeks and grandmother restarting Valproate in high dose. Response to the treatmentprovided to the patient was rewarding.]]>
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