Indian Journal of Forensic Medicine & Toxicology
Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology

Profile of Determinant Factors on Drug Allergy Severity in Indonesian Children at Dr. Soetomo General Academic Hospital, Surabaya, Indonesia

Bagas Triambodo (Unknown)
Azwin Mengindra Putera (Unknown)
Bambang Hermanto (Unknown)



Article Info

Publish Date
24 Mar 2021

Abstract

Background: Drug allergy in children is a rare case that needs special attention. Identifying the factorsthat affect the severity of drug allergy is important for the improvement of drug allergy management inIndonesian children. Objective: to analyze the factors that influence drug allergy severity in Indonesianchildren. Methods: This study used a retrospective design and consecutive sampling in 2014-2018. The datacollected included sex, types of allergy-causing drugs, previous allergy history, parental allergy history, andclinical manifestations. The data were analyzed by using a logistic regression test where the statistical testresults were significant if p <0.05. Results: The average age of the participants was 93.00 ± 50.54 monthswith a median value of 84 (12 - 204) months. Drug allergy severity in children is influenced by severalthings, such as the type of drug (? = 5.76; 95% CI 1.29 - 25.70; p = 0.022), sex (? = 1.27; 95% CI 0.30 - 5.36;p = 0.743), previous allergy history (? = 2.44; 95% CI 0.10 - 58.67; p = 0.583), and a drug allergy history onparents (? = 0.65; 95% CI 0.06 - 6.75; p = 0.719). Conclusion: There is a significant relationship betweendrug allergy severity and the type of drug whereas sex, previous allergy history, and a history of allergy onparents do not find a significant connection.

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