Indian Journal of Forensic Medicine & Toxicology
Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology

In Silico Study of SARS-CoV-2 Vaccine Candidate: Spike Glycoprotein

Arif Nur Muhammad Ansori (Unknown)



Article Info

Publish Date
24 Mar 2021

Abstract

This study aimed to perform the analysis of toxicity prediction, allergenicity prediction, and in silico cloningof peptides originated from SARS-CoV-2 spike glycoprotein in the previous study. Allergenicity predictionemployed AllerPred to predict the non-allergen peptides and toxicity prediction performed using ToxinPred.Then, this study designed the in silico cloning of SARS-CoV-2 spike glycoprotein with pET-28a(+) usingSnapGene software. Therefore, this study successfully constructed the SARS-CoV-2 vaccine candidate viain silico method. Therefore, these data could be used to design a peptide-based vaccine against SARSCoV-2. However, the advanced study is recommended confirmation, such as in vitro and in vivo study

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