Indian Journal of Forensic Medicine & Toxicology
Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology

Effect of Iron Deficiency Anemia on HbA1c Levels in Patients of Diabetes Mellitus with Controlled Plasma Glucose Levels

Smita N. Vasava (Unknown)
Roshni Sadaria (Unknown)
Tejas Shah (Unknown)



Article Info

Publish Date
24 Mar 2021

Abstract

Background: Hemoglobin A1C (HbA1c) is an indicator of patient’s glycemic status over the previous 3months. HbA1C levels increase in presence of Iron deficiency anemia.Aim: To analyze the effect of iron deficiency anemia on HbA1c levels in patients of diabetes mellitus withcontrolled plasma glucose levels.Material and Methods: In the present study, total 50 patient of diabetes mellitus with iron deficiencyanemia with controlled plasma glucose levels were taken as a cases and 50 iron-sufficient non-anemichealthy individuals were taken as a controls. Medical history was taken from all participant and data ofHbA1c, ferritin, FBS, hemoglobin, peripheral smear examination, red cell indices were collected fromlaboratory. Statistical analysis was carried out by student’s t-test, Chi-square test, and Pearson’s coefficientof regression.Results: HbA1C level (6.90 ± 0.81%) were increased in iron-deficient individuals as compared to controls.In females, HbA1C (7.08 ± 0.78%) were more elevated than males. When classified on the basis of FBS,HbA1C was elevated more in subjects having FBS between 100-126 mg/dl (7.31 ± 1.52%) compared to thethose with normal FBS (<100 mg/dl).Conclusion: A positive correlation found between iron deficiency anemia and increased HbA1C levels,especially in the controlled diabetic women and individuals having FBS between 100-126 mg/dl. Therefore,presence of iron deficiency anemia should be checked before altering the treatment regimen of diabetesmellitus patient.

Copyrights © 2021