Indian Journal of Forensic Medicine & Toxicology
Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology

Exosomes and their Role in Immunity, Metabolic, Cardiovascular, Neurodegeneration, Reproduction and Development

Zainab Abdullah Waheed (Unknown)
Nadia Habeeb Sarhan (Unknown)



Article Info

Publish Date
24 Mar 2021

Abstract

Exosomes are produced by an endocytic cellular route which consists of three steps:first: Cellular membranesinvagination forms the endocytic vesicles, then,The inward budding of the endosoma membrane starts atthe second level, and multivesicular bodies emerge.. In third and last step the multivascular bodies combinewith the cell membrane and Produces the substances of the vesicular, exosomes are used to transfer Setcell prostaglandins to specific cells exosomes Represent a new mode of contact between cells, which inmany biological processes may play a significant role, for example, immune response,Transduction ofsignals,antigen presentation- Intercellular communication mediated by exosome Cells usually communicatewith surrounding cells by direct cell-cell touch, involving interaction of the gap between the cell’s surfaceproteins and protein c interactions Communicate with regional cells via induction soluble Factors like:hormones as well as cytokines Improve the transmission of the signals, Electrical and chemical signals. Andalso Exosomes may play a role in the process of metabolic conditions and cardiovascular disorders theywere found to hold metabolites and allowing intra - cellular communication by exosomal miRNA exchangebetween skeletal muscles , adipose tissue, pancreatic b-cells, and the mouse liver and the human .

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