Synthesis, Characterization, and Preliminary Study of [Co(2- aminopyridine)2(NCS)2] or bis(2-aminopyridine)dithiocyanato cobalt(II) as An Antibacterial

Asmi Munadhiroh (Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Negeri Malang Jl. Semarang 5 Malang, 65145, Indonesia)
Husni Wahyu Wijaya (Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Negeri Malang Jl. Semarang 5 Malang, 65145, Indonesia)
Nani Farida (Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Negeri Malang Jl. Semarang 5 Malang, 65145, Indonesia)
Stéphane Golhen (Univ Rennes, CNRS, ISCR [(Institut des Sciences Chimiques de Rennes)] – UMR 6226, F-35000 Rennes, France)
I Wayan Dasna (Department of Chemistry Faculty of Mathematics andNatural Sciences Universitas Negeri Malang)

VALENSI
Jurnal Kimia VALENSI Volume 8, No. 1, May 2022

This study aims to synthesize complex compounds from the Co(II) ion with mixed ligands of 2-aminopyridine and thiocyanate ions. The complexes obtained have Co(II) : 2-aminopyridine: thiocyanate ratio of 1:2:2 based on preliminary analysis by SEM-EDX, DHL, and FTIR. The complex in the form of a blue needle crystal is stable at room temperature and melts at 169 °C. Characterization shows that the complex formed is neutral. The antibacterial activity test was carried out using the diffusion method and show that the resulting complex compounds could inhibit the growth of S. typhi and S. aureus bacteria better than 2-aminopyridine.