Indonesian Journal of Chemistry
ARTICLE IN PRESS

Antioxidant Flavonoid Glycoside from Leaves of Cacao Mistletoe (Scurrula ferruginea (Jack) Danser)

Mai Efdi (Department of Chemistry, Universitas Andalas, Kampus Limau Manis, Padang 25163, West Sumatra, Indonesia)
Dara Pratama (Department of Chemistry, Universitas Andalas, Kampus Limau Manis, Padang 25163, West Sumatra, Indonesia)
Afrizal Itam (Department of Chemistry, Universitas Andalas, Kampus Limau Manis, Padang 25163, West Sumatra, Indonesia)
Tia Okselni (Research Center for Pharmaceutical Ingredients and Traditional Medicine, National Research and Innovation Agency, Jl. Raya Bogor Km 46, Cibinong, Bogor 16911, West Java, Indonesia)



Article Info

Publish Date
02 Jun 2022

Abstract

Scurrula ferruginea (Jack) Danser is a folk medicine to treat several diseases. S. ferruginea is the mistletoe that lives by deriving nutrients from the host. Hence, the host has a significant effect on the biological activities and bioactive components of S. ferruginea. In this study, the leaves of S. ferruginea were macerated by methanol solvent to extract the chemical components and fractionated by hexane and ethyl acetate solvent, respectively, to separate organic compounds. The biological activity of crude extracts as the antioxidant was investigated by 2,2-diphenyl-1-picrylhydrazyl (DPPH) method. The result showed that the highest antioxidant activity was obtained from the ethyl acetate fraction with the IC50 of 10.88 ± 0.39 µg/mL. Furthermore, the trituration method used several solvents to isolate secondary metabolites from the initial crude methanol extract. This purification process produced a flavonoid compound of quercitrin. The antioxidant activity of quercitrin was also determined by the DPPH method. The result showed that this compound has stronger activity than the crude extracts with the IC50 of 5.95 ± 0.11 µg/mL. This study demonstrated that cacao mistletoe of S. ferruginea may have the potential activity to treat the diseases caused by the presence of free radicals.

Copyrights © 0000






Journal Info

Abbrev

ijc

Publisher

Subject

Chemical Engineering, Chemistry & Bioengineering Chemistry

Description

Indonesian Journal of Chemistry is an International, peer-reviewed, open access journal that publishes original research articles, review articles, as well as short communication in all areas of chemistry including applied chemistry. The journal is accredited by The Ministry of Research, Technology ...