Jurnal Ilmiah Berkala: Sains dan Terapan Kimia
Vol 6, No 1 (2012)

SINTESIS 3,3'-DI(5-BROMO-N-METILINDOL-3-IL)-5-BROMOINDOLIN-2-ONA DAN UJI SITOTOKSISITASNYA TERHADAP SEL VERO

Kamilia Mustikasari (Unknown)
Mardi Santoso (Unknown)

Article Info

Publish Date
18 Oct 2016

Abstract

Telah berhasil disintesis senyawa trisindolina baru: 3,3'-di(5-bromo-N- metilindol-3-il)-5-bromoindolin-2-ona melalui reaksi substitusi aromatik elektrofilik 5-bromo-N-metilindola dengan 5-bromoisatin pada kondisi asam dengan rendemen 53% yang tidak sitotoksik terhadap sel normal (sel Vero). Metilasi 5-bromoindola menghasilkan 5-bromo-N-metilindola dengan rendemen 87%. Kata kunci: sintesis, turunan 3,3'-di(indol-3-il)indolin-2-ona, sitotoksisitas 

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Journal Info
Jurnal Ilmiah Berkala: Sains dan Terapan Kimia
Website

Abbrev

jstk

Publisher

Universitas Lambung Mangkurat

Subject

Chemical Engineering, Chemistry & Bioengineering Chemistry

Description

Sains dan Terapan Kimia (Jurnal Ilmiah Berkala) published scientific articles in the Chemistry field which include, but not limited to, research in chemistry, theoretical chemistry, chemistry education, and applied chemistry. This journal also published review articles about the development of ...