Oceana Biomedicina Journal
Vol 2 No 2 (2019): Oceana Biomedicina Journal Volume 2 Issue (No) 2 July - December 2019

Pengaruh Pemberian Terapi Oksigen Hiperbarik 2,4 ATA terhadap Kadar C-Reactive Protein (CRP) Darah Mencit Model Rheumatoid Arthritis

Thalia Tamara (Undergraduate Student of Fakultas Kedokteran Universitas Hang Tuah)
Hendrata Erry Andisari (Fakultas Kedokteran Universitas Hang Tuah)
Totot Mudjiono (RSPAL dr. Ramelan, Surabaya)



Article Info

Publish Date
05 Jul 2019

Abstract

Background: Rheumatoid Arthritis (RA) is an autoimmune disease with an increasingprevalence from year to year. RA mortality continues to increase in the last 1 decade due tothe absence of effective prevention and therapy. Hyperbaric oxygen therapy can be anadjuvant therapy for Rheumathoid Arthritis.Objective: This study uses Hyperbaric Oxygen Therapy to reduce the inflammatory reactionin patients with Rheumatoid Arthritis.Method: Samples used are 16 male balb/c mice, divided into 2 groups, 1) group of inducedexperimental animals as models of Rheumatoid Arthritis 2) group of induced experimentalanimals as models of Rheumatoid Arthritis and given 3x30 minutes of 2.4 ATA hyperbaricoxygen therapy for 10 consecutive days. On 59th day, ELISA screening test is performed forC-ReactiveProtein measurement.Result: The average results of C-Reactive Protein levels between 2 groups, are, the group ofmice with rheumatoid arthritis model that was not treated with HBO therapy had an averageCRP level of 0.204 Pg / ml, while the group of mice with rheumatoid arthritis model which istreated with HBO therapy has a mean CRP level of 0.113 Pg / ml.Conclusion: There is an effect of hyperbaric oxygen therapy to C-Reactive Protein level inmice with rheumatoid arthritis model.

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Journal Info

Abbrev

jurnal

Publisher

Subject

Dentistry Health Professions Medicine & Pharmacology Nursing Public Health

Description

Oceana Biomedicina Journal is an open access journal of health and medicine. Specifically, the journal focuses on marine medicine, hyperbaric medicine and health, medicine on ships, harbor health, maritime and coastal health, medicolegal studies related to ships, ports and districts, ...